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Catalog Number:
33586
CAS Number:
1217627-86-5
Fmoc-D-2,4-diméthylphénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Phe(2,4-DiCH3)-OH, Acide Fmoc-( R )-2-amino-3-(2,4-diméthylphényl)propionique
Documents
$75.50 /100 mg
Taille
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Product Information

Fmoc-D-2,4-dimethylphenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 2,4-dimethylphenyl side chain, enhances the hydrophobic interactions in peptide chains, making it particularly useful in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its ability to improve the stability and solubility of peptides, facilitating the development of therapeutic agents with enhanced efficacy.

In practical applications, Fmoc-D-2,4-dimethylphenylalanine is commonly employed in solid-phase peptide synthesis (SPPS), where it contributes to the formation of complex peptide sequences. Its use in combinatorial chemistry also allows for the rapid generation of peptide libraries, aiding in drug discovery and development. The compound's favorable properties make it an excellent choice for researchers looking to optimize peptide synthesis and enhance the biological activity of their compounds.

Synonyms
Fmoc-D-Phe(2,4-DiCH3)-OH, Acide Fmoc-( R )-2-amino-3-(2,4-diméthylphényl)propionique
CAS Number
1217627-86-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 26 H 254
Molecular Weight
415.48
MDL Number
MFCD06659133
PubChem ID
11589726
Melting Point
121 - 127?C
Appearance
Poudre blanche
Optical Rotation
[a]D25 = 39 ± 1 ° (C=1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Fmoc-D-Phe(2,4-DiCH3)-OH, Acide Fmoc-( R )-2-amino-3-(2,4-diméthylphényl)propionique
CAS Number
1217627-86-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 26 H 254
Molecular Weight
415.48
MDL Number
MFCD06659133
PubChem ID
11589726
Melting Point
121 - 127?C
Appearance
Poudre blanche
Optical Rotation
[a]D25 = 39 ± 1 ° (C=1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-D-2,4-dimethylphenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences efficiently.
  • Drug Development: Its unique structure helps in designing peptide-based drugs, particularly in targeting specific receptors, enhancing therapeutic efficacy in pharmaceuticals.
  • Bioconjugation: The Fmoc protecting group facilitates the attachment of biomolecules, making it valuable in developing targeted drug delivery systems in cancer therapy.
  • Research in Neuroscience: It is used in the synthesis of neuropeptides, aiding studies on neurotransmission and potential treatments for neurological disorders.
  • Material Science: The compound can be incorporated into polymer matrices, contributing to the development of smart materials with responsive properties for various applications.

Citations