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Catalog Number:
33483
CAS Number:
187283-25-6
Fmoc-L-Phe(4-guanidino-Boc 2 )-OH
Purity:
≥ 97 % (HPLC)
Synonym(s):
Fmoc-4-(N,N'-di-Boc-guanidino)-L-phénylalanine, Fmoc-4-bis(t-butyloxycarbonyl)guanidino-L-phénylalanine
Documents
$60.00 /100 mg
Taille
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Product Information

Fmoc-L-Phe(4-guanidino-Boc2)-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability and ease of removal under mild conditions, making it ideal for solid-phase peptide synthesis. The presence of the guanidino group enhances its functionality, allowing for the incorporation of unique structural features into peptides, which can be pivotal in the design of bioactive compounds and therapeutic agents.

Researchers and industry professionals utilize Fmoc-L-Phe(4-guanidino-Boc2)-OH in various applications, including the development of peptide-based drugs, protein engineering, and the synthesis of complex biomolecules. Its ability to facilitate the introduction of guanidino functionalities can lead to improved binding affinities and biological activities, making it a valuable tool in medicinal chemistry and biochemistry. With its unique properties and practical applications, this compound stands out as a significant asset for those engaged in advanced chemical research and pharmaceutical development.

Synonyms
Fmoc-4-(N,N'-di-Boc-guanidino)-L-phénylalanine, Fmoc-4-bis(t-butyloxycarbonyl)guanidino-L-phénylalanine
CAS Number
187283-25-6
Purity
≥ 97 % (HPLC)
Molecular Formula
C35H40N4O8
Molecular Weight
644.7
MDL Number
MFCD02092975
PubChem ID
135480908
Appearance
Poudre cristalline blanche
Optical Rotation
[a] D 20 = 12 ± 1 ° (C = 1 dans MeOH)
Conditions
Conserver entre -15 et -25 °C
General Information
Synonyms
Fmoc-4-(N,N'-di-Boc-guanidino)-L-phénylalanine, Fmoc-4-bis(t-butyloxycarbonyl)guanidino-L-phénylalanine
CAS Number
187283-25-6
Purity
≥ 97 % (HPLC)
Molecular Formula
C35H40N4O8
Molecular Weight
644.7
MDL Number
MFCD02092975
PubChem ID
135480908
Appearance
Poudre cristalline blanche
Optical Rotation
[a] D 20 = 12 ± 1 ° (C = 1 dans MeOH)
Conditions
Conserver entre -15 et -25 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-Phe(4-guanidino-Boc2)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development.
  • Drug Design: Its unique guanidino group enhances interactions with biological targets, making it valuable in the design of novel therapeutics, particularly in oncology and infectious diseases.
  • Bioconjugation: The compound can be used to attach biomolecules to surfaces or other compounds, facilitating the development of targeted drug delivery systems and diagnostic tools.
  • Research in Protein Engineering: It aids in the modification of proteins to study their functions and interactions, providing insights that are crucial for understanding disease mechanisms.
  • Development of Biopharmaceuticals: Its properties support the formulation of biologically active compounds, enhancing stability and efficacy in therapeutic applications.

Citations