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Catalog Number:
33462
CAS Number:
2250436-47-4
Acide N α - Fmoc- N β -pentynoyl-2,3-diaminopropionique
Purity:
≥ 98 % (dosage par titration, HPLC)
Synonym(s):
Fmoc-L-Dap(pentynoyl)-OH, ( Acide S -2-{[(9 H -Fluoren-9-ylméthyloxy)carbonyl]amino}-3-(pent-4-ynamido)propanoïque
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$106.96 /100 mg
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Product Information

Na-Fmoc-Nb-pentynoyl-2,3-diaminopropionic acid is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique pentynoyl side chain enhances its reactivity and allows for the incorporation of alkyne functionalities, making it particularly valuable in click chemistry applications. Researchers in medicinal chemistry and biochemistry can leverage this compound for the development of novel therapeutics and biomolecules, facilitating the creation of complex peptide structures with enhanced biological activity.

The compound's ability to undergo selective reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC), positions it as a key player in the synthesis of bioconjugates and targeted drug delivery systems. Its stability and compatibility with various coupling reagents further enhance its utility in laboratory settings. With its robust profile, Na-Fmoc-Nb-pentynoyl-2,3-diaminopropionic acid is an essential tool for researchers aiming to innovate in peptide-based therapies and materials science.

Synonyms
Fmoc-L-Dap(pentynoyl)-OH, ( Acide S -2-{[(9 H -Fluoren-9-ylméthyloxy)carbonyl]amino}-3-(pent-4-ynamido)propanoïque
CAS Number
2250436-47-4
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C23H22N2O5
Molecular Weight
406.4
MDL Number
MFCD00072199
PubChem ID
170999905
Melting Point
128 - 135 ?C
Appearance
Poudre cristalline blanche
Optical Rotation
[a] 20 D = -28 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Fmoc-L-Dap(pentynoyl)-OH, ( Acide S -2-{[(9 H -Fluoren-9-ylméthyloxy)carbonyl]amino}-3-(pent-4-ynamido)propanoïque
CAS Number
2250436-47-4
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C23H22N2O5
Molecular Weight
406.4
MDL Number
MFCD00072199
PubChem ID
170999905
Melting Point
128 - 135 ?C
Appearance
Poudre cristalline blanche
Optical Rotation
[a] 20 D = -28 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Na-Fmoc-Nb-pentynoyl-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing for the selective modification of amino acids. It enhances the efficiency of creating complex peptides, which are crucial in drug development.
  • Drug Development: Its unique structure aids in the design of novel therapeutic agents, particularly in oncology and infectious diseases, by facilitating the development of targeted drug delivery systems.
  • Bioconjugation: The chemical is employed in bioconjugation techniques, linking biomolecules to therapeutic agents, which is essential in creating more effective and specific treatments.
  • Research in Neuroscience: It is used in the synthesis of neuropeptides, contributing to the understanding of neurological functions and the development of treatments for neurodegenerative diseases.
  • Material Science: The compound finds applications in creating functionalized polymers, which can be used in drug delivery systems and advanced materials with tailored properties.

Citations