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Catalog Number:
33039
CAS Number:
138068-37-8
Acétate de lépirudine
Synonym(s):
H-Leu-Thr-Tyr-Thr-Asp-Cys-Thr-Glu-Ser-Gly-Gln-Asn-Leu-Cys-Leu-Cys-Glu-Gly-Ser-Asn-Val-Cys-Gly-Gln-Gly-Asn-Lys-Cys-Ile-Leu-Gly-Ser-Asp-Gly-Glu-Lys-Asn-Gln-Cys-Val-Thr-Gly-Glu-Gly-Thr-Pro-Lys-Pro-Gln-Ser-His-Asn-Asp-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OHel d'acétate, (Leu1,Thr2)-Hirudine (désulfatée)
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$1,553.73 /1MG
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Product Information

Lepirudin acetate salt is a potent anticoagulant derived from the saliva of the medicinal leech, Hirudo medicinalis. This compound is primarily utilized in the medical field for its ability to inhibit thrombin, making it an essential agent in the management of patients with heparin-induced thrombocytopenia (HIT). Its unique mechanism of action allows for effective anticoagulation without the risk of heparin-related complications, providing a safer alternative for patients requiring anticoagulation therapy. Lepirudin is particularly beneficial in clinical settings where rapid anticoagulation is necessary, such as during percutaneous coronary interventions or in patients with a history of thrombosis.

In addition to its therapeutic applications, Lepirudin acetate salt is also valuable in research settings, particularly in studies focused on coagulation pathways and thrombin inhibition. Its specificity for thrombin makes it an ideal candidate for investigating the mechanisms of blood coagulation and the development of novel anticoagulant therapies. Researchers and healthcare professionals appreciate Lepirudin for its reliability and effectiveness, positioning it as a critical tool in both clinical and laboratory environments.

Synonyms
H-Leu-Thr-Tyr-Thr-Asp-Cys-Thr-Glu-Ser-Gly-Gln-Asn-Leu-Cys-Leu-Cys-Glu-Gly-Ser-Asn-Val-Cys-Gly-Gln-Gly-Asn-Lys-Cys-Ile-Leu-Gly-Ser-Asp-Gly-Glu-Lys-Asn-Gln-Cys-Val-Thr-Gly-Glu-Gly-Thr-Pro-Lys-Pro-Gln-Ser-His-Asn-Asp-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OHel d'acétate, (Leu1,Thr2)-Hirudine (désulfatée)
CAS Number
138068-37-8
Molecular Formula
C 287 H 440 N 80 O 111 S 6 · C 2 H 4 O 2
Molecular Weight
7039.57
MDL Number
MFCD09970571
PubChem ID
139600825
Conditions
Conserver à ≤ -10 °C
General Information
Synonyms
H-Leu-Thr-Tyr-Thr-Asp-Cys-Thr-Glu-Ser-Gly-Gln-Asn-Leu-Cys-Leu-Cys-Glu-Gly-Ser-Asn-Val-Cys-Gly-Gln-Gly-Asn-Lys-Cys-Ile-Leu-Gly-Ser-Asp-Gly-Glu-Lys-Asn-Gln-Cys-Val-Thr-Gly-Glu-Gly-Thr-Pro-Lys-Pro-Gln-Ser-His-Asn-Asp-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OHel d'acétate, (Leu1,Thr2)-Hirudine (désulfatée)
CAS Number
138068-37-8
Molecular Formula
C 287 H 440 N 80 O 111 S 6 · C 2 H 4 O 2
Molecular Weight
7039.57
MDL Number
MFCD09970571
PubChem ID
139600825
Conditions
Conserver à ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Lepirudin acetate salt is widely utilized in research focused on:

  • Anticoagulant Therapy: This compound is primarily used as a direct thrombin inhibitor in patients with heparin-induced thrombocytopenia (HIT), providing a safer alternative to traditional anticoagulants.
  • Cardiovascular Research: It plays a crucial role in studies related to cardiovascular diseases, helping researchers understand thrombus formation and the efficacy of anticoagulation strategies.
  • Pharmaceutical Development: Lepirudin is significant in the development of new anticoagulant drugs, allowing pharmaceutical companies to innovate safer and more effective treatments.
  • Clinical Trials: It is frequently used in clinical trials to evaluate the safety and effectiveness of new anticoagulant therapies, contributing to advancements in medical treatments.
  • Laboratory Research: In laboratory settings, it aids in various assays and experiments to study blood coagulation mechanisms, enhancing the understanding of hemostasis and thrombosis.

Citations