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Catalog Number:
33035
CAS Number:
64297-16-1
Nle 8,18 , Tyr 34 -pTH (3-34) amide (bovin)
Synonym(s):
H-Ser-Glu-Ile-Gln-Phe-Nle-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Nle-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2, [Nle8,18, Tyr34] Hormone parathyroïdienne (3-34), amide, bovine
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Product Information

(Nle8,18, Tyr34)-pTH (3-34) amide (bovine) is a synthetic peptide derived from parathyroid hormone, specifically designed for research and therapeutic applications in the field of endocrinology and bone metabolism. This compound plays a crucial role in the regulation of calcium and phosphate homeostasis, making it an essential tool for researchers investigating bone density, osteoporosis, and related disorders. Its unique structure, which includes non-natural amino acids, enhances its stability and bioactivity compared to traditional parathyroid hormone formulations.

In practical applications, (Nle8,18, Tyr34)-pTH (3-34) amide has been utilized in studies focusing on bone regeneration and repair, as well as in the development of novel osteoporosis treatments. Its ability to stimulate osteoblast activity and inhibit osteoclast formation positions it as a valuable candidate for therapeutic interventions aimed at enhancing bone health. Researchers and industry professionals can leverage this compound to explore innovative solutions for managing bone-related diseases, ultimately contributing to improved patient outcomes.

Synonyms
H-Ser-Glu-Ile-Gln-Phe-Nle-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Nle-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2, [Nle8,18, Tyr34] Hormone parathyroïdienne (3-34), amide, bovine
CAS Number
64297-16-1
Molecular Formula
C 177 H 279 N 53 O 48
Molecular Weight
3917.49
MDL Number
MFCD00081229
Conditions
Conserver à ≤ -10 °C
General Information
Synonyms
H-Ser-Glu-Ile-Gln-Phe-Nle-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Nle-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2, [Nle8,18, Tyr34] Hormone parathyroïdienne (3-34), amide, bovine
CAS Number
64297-16-1
Molecular Formula
C 177 H 279 N 53 O 48
Molecular Weight
3917.49
MDL Number
MFCD00081229
Conditions
Conserver à ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(Nle8,18, Tyr34)-pTH (3-34) amide (bovine) is widely utilized in research focused on

  • Endocrine Research: This compound is instrumental in studying the effects of parathyroid hormone on calcium metabolism, making it valuable for researchers investigating bone health and metabolic disorders.
  • Pharmaceutical Development: It serves as a lead compound in the development of new drugs aimed at treating osteoporosis and other bone-related diseases, providing a basis for creating more effective therapies.
  • Biotechnology: In the biotech industry, it is used in the formulation of recombinant proteins, enhancing the production of therapeutic agents that mimic natural hormone functions.
  • Diagnostic Applications: The compound is utilized in assays and diagnostic kits for measuring parathyroid hormone levels in clinical settings, aiding in the diagnosis of various endocrine disorders.
  • Research on Aging: It plays a role in studies related to aging and bone density, helping researchers understand how hormonal changes affect bone health over time.

Citations