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Catalog Number:
32899
CAS Number:
219137-91-4
Z-Val-Ala-Asp-AMC
Synonym(s):
["["Bis(1, 1-diméthyléthyl)azodicarboxylate, [DBAD »]
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$200.30 /5 mg
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Product Information

Z-Val-Ala-Asp-AMC is a synthetic peptide substrate widely utilized in biochemical research and drug development. This compound, also known as Z-Val-Ala-Asp-7-amido-4-methylcoumarin, is particularly valuable for studying protease activity due to its specificity for certain enzymes. Researchers often employ Z-Val-Ala-Asp-AMC in assays to monitor the activity of caspases and other proteases, making it an essential tool in apoptosis research and cancer studies. Its unique structure allows for the release of a fluorescent signal upon cleavage, enabling sensitive detection and quantification of enzyme activity.

In addition to its applications in basic research, Z-Val-Ala-Asp-AMC has potential uses in the development of therapeutic agents targeting proteolytic pathways. Its ability to serve as a substrate in high-throughput screening assays makes it an attractive option for pharmaceutical companies looking to identify novel inhibitors or modulators of protease activity. By incorporating Z-Val-Ala-Asp-AMC into their workflows, researchers can enhance their understanding of protease functions and their implications in various diseases, ultimately contributing to the advancement of targeted therapies.

Synonyms
["["Bis(1, 1-diméthyléthyl)azodicarboxylate, [DBAD »]
CAS Number
219137-91-4
Molecular Formula
C30H34N4O9
Molecular Weight
594.62
MDL Number
MFCD01318828
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
["["Bis(1, 1-diméthyléthyl)azodicarboxylate, [DBAD »]
CAS Number
219137-91-4
Molecular Formula
C30H34N4O9
Molecular Weight
594.62
MDL Number
MFCD01318828
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Z-Val-Ala-Asp-AMC is widely utilized in research focused on:

  • Protease Activity Assays: This compound serves as a substrate for various proteases, allowing researchers to measure enzyme activity in biological samples, which is crucial for understanding disease mechanisms.
  • Drug Development: It plays a role in screening potential drug candidates by evaluating their effects on proteolytic enzymes, helping pharmaceutical companies identify effective treatments.
  • Cell Signaling Studies: The compound is used to investigate cellular signaling pathways, providing insights into how cells communicate and respond to external stimuli, which is vital for cancer research.
  • Biomarker Discovery: Researchers utilize it to identify and validate biomarkers for various diseases, enhancing diagnostic and therapeutic strategies in clinical settings.
  • Peptide Synthesis: This chemical aids in the synthesis of peptides, which are essential for developing new therapeutic agents and understanding protein interactions.

Citations