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Catalog Number:
32606
CAS Number:
348086-66-8
Z-Leu-Leu-Glu-AMC
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$273.61 /5 mg
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Product Information

Z-Leu-Leu-Glu-AMC is a highly specialized peptide substrate that plays a crucial role in biochemical research, particularly in the study of proteases and enzyme activity. This compound is recognized for its ability to serve as a fluorogenic substrate, allowing researchers to monitor proteolytic activity in real-time. Its unique structure, featuring leucine and glutamic acid residues, enhances its specificity and sensitivity in various assays, making it an invaluable tool in drug discovery and development.

In practical applications, Z-Leu-Leu-Glu-AMC is widely utilized in the fields of molecular biology and biochemistry, particularly in the development of assays for cancer research and therapeutic interventions. Its ability to provide clear, quantifiable results makes it a preferred choice for researchers looking to explore enzyme kinetics and protease inhibition. By incorporating Z-Leu-Leu-Glu-AMC into experimental protocols, scientists can gain deeper insights into cellular processes and disease mechanisms, ultimately contributing to advancements in medical research and therapeutic strategies.

CAS Number
348086-66-8
Molecular Formula
Z-Leu-Leu-Glu-AMC
Molecular Weight
664.76
MDL Number
MFCD01074989
PubChem ID
44135170
Conditions
Conserver entre 2 et 8 °C
General Information
CAS Number
348086-66-8
Molecular Formula
Z-Leu-Leu-Glu-AMC
Molecular Weight
664.76
MDL Number
MFCD01074989
PubChem ID
44135170
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Z-Leu-Leu-Glu-AMC is widely utilized in research focused on:

  • Protease Activity Assays: This compound serves as a substrate in assays to measure the activity of proteases, which are crucial for various biological processes. Its specificity allows researchers to study enzyme kinetics effectively.
  • Drug Development: In pharmaceutical research, Z-Leu-Leu-Glu-AMC is used to screen potential drug candidates that target proteolytic enzymes, aiding in the development of therapies for diseases like cancer and neurodegenerative disorders.
  • Biochemical Research: It plays a significant role in studying protein interactions and post-translational modifications, helping scientists understand cellular mechanisms and signaling pathways.
  • Diagnostic Applications: This compound can be utilized in diagnostic kits to detect protease-related diseases, providing a valuable tool for early diagnosis and monitoring of conditions.
  • Research on Protein Folding: Z-Leu-Leu-Glu-AMC is instrumental in studies investigating protein folding and misfolding, which are critical in understanding various diseases, including Alzheimer's and Parkinson's.

Citations