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Catalog Number:
32499
CAS Number:
27848-84-6
Nicergoline
Purity:
≥ 98 % (HPLC, T)
Synonym(s):
Ester méthylique 10-méthoxy-1,6-diméthylergoline-8-de l'acide 5-bromonicotinique, [(8 R ,10 S )-10-méthoxy-1,6-diméthylergolin-8-yl]méthyl5-bromopyridine-3-carboxylate
Documents
$65.40 /250 mg
Taille
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Informations sur le produit

La nicergoline est un dérivé de l'ergot de seigle et un vasodilatateur qui augmente le flux sanguin dans le cerveau ! Conserver à l'abri des agents oxydants.

Numéro CAS 
27848-84-6
Formule moléculaire
C24H26BrN3O3
Poids moléculaire 
484.39
Point de fusion 
134 - 138 °C
Rotation optique 
[a]20/D= +5,2 à +6,2° (C=5 dans EtOH(95vol%))
Informations générales
Numéro CAS 
27848-84-6
Formule moléculaire
C24H26BrN3O3
Poids moléculaire 
484.39
Point de fusion 
134 - 138 °C
Rotation optique 
[a]20/D= +5,2 à +6,2° (C=5 dans EtOH(95vol%))
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Nicergoline is widely utilized in research focused on:

  • Cognitive Enhancement: This compound is often studied for its potential to improve cognitive function, particularly in elderly patients suffering from cognitive decline. Researchers explore its effects on memory and attention, making it relevant in geriatric medicine.
  • Vascular Health: Nicergoline is known for its vasodilatory properties, which help improve blood flow. This application is beneficial in treating conditions like peripheral vascular disease, where enhanced circulation can alleviate symptoms.
  • Neuroprotective Effects: Studies indicate that Nicergoline may protect neurons from damage, making it a subject of interest in neurodegenerative disease research, such as Alzheimer's and Parkinson's disease.
  • Ophthalmology: The compound is explored for its potential benefits in treating age-related macular degeneration (AMD) by improving retinal blood flow, which is crucial for maintaining vision in older adults.
  • Pharmaceutical Formulations: Nicergoline is often included in various formulations aimed at enhancing cognitive function and improving quality of life in patients with vascular-related cognitive impairment, showcasing its versatility in the pharmaceutical industry.

Citations