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Catalog Number:
31974
CAS Number:
957509-29-4
Fmoc -O - tert -butyl-L-β-homohydroxyproline
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-β-HomoHyp(tBu)-OH, Acide 2-[(2S,4R)-1-(9h-fluorén-9-ylméthoxycarbonyl)-4-[(2-méthylpropan-2-yl)oxy]pyrrolidin-2-yl]acétique
Documents
$221.63 /100 mg
Taille
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Product Information

Fmoc-O-tert-butyl-L-b-homohydroxyproline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the field of medicinal chemistry. Its unique tert-butyl group enhances solubility and stability, facilitating smoother reactions and improved yields in peptide coupling reactions.

Researchers and industry professionals benefit from using Fmoc-O-tert-butyl-L-b-homohydroxyproline in the design of bioactive peptides, particularly those targeting specific biological pathways. Its application extends to the development of pharmaceuticals, where it plays a crucial role in creating compounds with enhanced efficacy and reduced side effects. The compound's ability to provide structural diversity in peptide libraries makes it invaluable for drug discovery and development, ensuring that researchers can explore a wide range of therapeutic possibilities.

Synonyms
Fmoc-β-HomoHyp(tBu)-OH, Acide 2-[(2S,4R)-1-(9h-fluorén-9-ylméthoxycarbonyl)-4-[(2-méthylpropan-2-yl)oxy]pyrrolidin-2-yl]acétique
CAS Number
957509-29-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H29NO5
Molecular Weight
423.51
MDL Number
MFCD01862868
PubChem ID
4158447
Appearance
Solide blanc à blanc cassé
Optical Rotation
[a] 20 D = -22 ± 2 º (C=1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-β-HomoHyp(tBu)-OH, Acide 2-[(2S,4R)-1-(9h-fluorén-9-ylméthoxycarbonyl)-4-[(2-méthylpropan-2-yl)oxy]pyrrolidin-2-yl]acétique
CAS Number
957509-29-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H29NO5
Molecular Weight
423.51
MDL Number
MFCD01862868
PubChem ID
4158447
Appearance
Solide blanc à blanc cassé
Optical Rotation
[a] 20 D = -22 ± 2 º (C=1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-O-tert-butyl-L-b-homohydroxyproline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity and yield.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific biological pathways, due to its ability to modify peptide sequences effectively.
  • Bioconjugation: The compound is used in bioconjugation processes, which involve attaching biomolecules to other molecules, enhancing the efficacy of therapeutic agents and improving drug delivery systems.
  • Research in Protein Engineering: Researchers utilize this chemical in protein engineering to create novel proteins with desired properties, aiding in the development of new biocatalysts and therapeutic proteins.
  • Cosmetic Formulations: Its application extends to the cosmetic industry, where it is used in formulations aimed at improving skin hydration and texture, leveraging its biochemical properties for enhanced skin benefits.

Citations