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Catalog Number:
30536
CAS Number:
702679-55-8
Acide (2 S ,4 R )-Fmoc-4-azido-pyrrolidine-2-carboxylique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-(4 R )-azido-L-Proline, Fmoc-(2 S ,4 R )-4-azidoproline
Antibiotic
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$100.00 /100 mg
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Product Information

Fmoc-(4R)-azido-L-Proline is a versatile building block widely utilized in peptide synthesis and drug discovery. This compound features a unique azido group that enhances its reactivity, making it an excellent candidate for click chemistry applications. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Researchers appreciate its role in the development of bioactive peptides and in the modification of proteins, enabling the exploration of new therapeutic avenues.

In addition to its applications in synthetic chemistry, Fmoc-(4R)-azido-L-Proline is particularly valuable in the field of medicinal chemistry, where it can be employed to create peptide-based drugs with improved efficacy and selectivity. Its unique properties facilitate the introduction of functional groups, allowing for the design of complex molecular architectures. This compound stands out among similar products due to its ease of use and the efficiency it brings to peptide synthesis, making it an essential tool for researchers and industry professionals alike.

Synonyms
Fmoc-(4 R )-azido-L-Proline, Fmoc-(2 S ,4 R )-4-azidoproline
CAS Number
702679-55-8
Purity
≥ 99 % (HPLC)
Molecular Formula
C20H18N4O4
Molecular Weight
378.4
MDL Number
MFCD21363169
PubChem ID
21467060
Appearance
Poudre cristalline blanche à blanc cassé
Optical Rotation
[a] D 20 = -35 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-(4 R )-azido-L-Proline, Fmoc-(2 S ,4 R )-4-azidoproline
CAS Number
702679-55-8
Purity
≥ 99 % (HPLC)
Molecular Formula
C20H18N4O4
Molecular Weight
378.4
MDL Number
MFCD21363169
PubChem ID
21467060
Appearance
Poudre cristalline blanche à blanc cassé
Optical Rotation
[a] D 20 = -35 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Oui
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(4R)-azido-L-Proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development and biological studies.
  • Bioconjugation: Its azido group enables efficient bioconjugation reactions, making it valuable for attaching biomolecules to surfaces or other molecules, enhancing the functionality of therapeutic agents.
  • Drug Discovery: In medicinal chemistry, it is used to explore new drug candidates by modifying existing compounds, improving their efficacy and selectivity against target diseases.
  • Protein Labeling: The compound can be employed in protein labeling techniques, facilitating the study of protein interactions and dynamics in various biological systems.
  • Research in Chemical Biology: It plays a significant role in chemical biology for the development of novel probes and tools, aiding in the understanding of cellular processes and disease mechanisms.

Citations