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Catalog Number:
30530
CAS Number:
1263047-53-5
Acide N α -Fmoc-N γ -Azido-D-2,4-diaminobutyrique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Acide (2 R )-4-azido-2-(Fmoc-amino)butanoïque, Fmoc-D-Dab(N3)-OH, Fmoc-D-azidohomoalanine
Antibiotic
Documents
$66.80 /100 mg
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Product Information

Na-Fmoc-Ng-Azido-D-2,4-diaminobutyric acid is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective deprotection of amines during solid-phase peptide synthesis. The azido group enhances its utility in click chemistry, allowing for efficient conjugation with various biomolecules, making it an essential tool for researchers in medicinal chemistry and drug development. Its unique structure not only facilitates the synthesis of complex peptides but also opens avenues for the development of novel therapeutics and diagnostic agents.

This compound is particularly beneficial in the fields of biochemistry and molecular biology, where it can be employed to create targeted drug delivery systems and study protein interactions. Its stability and reactivity under physiological conditions make it an attractive choice for researchers looking to explore new therapeutic strategies. With its ability to streamline peptide synthesis and enhance bioconjugation efficiency, Na-Fmoc-Ng-Azido-D-2,4-diaminobutyric acid stands out as a valuable asset in the toolkit of modern chemical research.

Synonyms
Acide (2 R )-4-azido-2-(Fmoc-amino)butanoïque, Fmoc-D-Dab(N3)-OH, Fmoc-D-azidohomoalanine
CAS Number
1263047-53-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.4
MDL Number
MFCD13184927
PubChem ID
74396372
Melting Point
122 - 128 °C
Appearance
Poudre cristalline blanche
Optical Rotation
[a] D 20 = 29 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Acide (2 R )-4-azido-2-(Fmoc-amino)butanoïque, Fmoc-D-Dab(N3)-OH, Fmoc-D-azidohomoalanine
CAS Number
1263047-53-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.4
MDL Number
MFCD13184927
PubChem ID
74396372
Melting Point
122 - 128 °C
Appearance
Poudre cristalline blanche
Optical Rotation
[a] D 20 = 29 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Oui
DEA-regulated
Non
Warnings
-
Applications

Na-Fmoc-Ng-Azido-D-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development.
  • Bioconjugation: Its azido group enables efficient bioconjugation reactions, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted therapies.
  • Drug Development: The compound's unique structure can lead to the creation of novel therapeutic agents, particularly in oncology, where targeted treatments are increasingly important.
  • Research in Chemical Biology: It is used in studies that explore protein interactions and functions, helping scientists understand biological processes at a molecular level.
  • Fluorescent Labeling: The Fmoc group allows for easy incorporation into fluorescent labeling techniques, enhancing imaging and tracking of biological molecules in research.

Citations