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Catalog Number:
29717
CAS Number:
884880-39-1
( R -Fmoc-β-hydroxy-valine
Purity:
≥ 99 % (HPLC)
Synonym(s):
( Acide R -Fmoc-2-amino-3-hydroxy-3-méthyl-butyrique, ( R -Fmoc-β-diméthyl-sérine
Documents
$106.96 /25 mg
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Product Information

(R)-Fmoc-b-hydroxy-valine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances the stability of the peptide chains but also facilitates the introduction of hydroxyl groups, making it an essential building block in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its role in enhancing solubility and bioavailability, which are critical factors in drug formulation.

In addition to its applications in medicinal chemistry, (R)-Fmoc-b-hydroxy-valine is also employed in the development of peptide-based therapeutics, particularly in the fields of oncology and infectious diseases. Its ability to improve the pharmacokinetic properties of peptides makes it a valuable asset for researchers aiming to create more effective therapeutic agents. With its proven track record in enhancing peptide synthesis and drug efficacy, (R)-Fmoc-b-hydroxy-valine stands out as a key compound for professionals in the pharmaceutical and biochemistry sectors.

Synonyms
( Acide R -Fmoc-2-amino-3-hydroxy-3-méthyl-butyrique, ( R -Fmoc-β-diméthyl-sérine
CAS Number
884880-39-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 215
Molecular Weight
355.39
MDL Number
MFCD02682577
PubChem ID
46737422
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +16 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
( Acide R -Fmoc-2-amino-3-hydroxy-3-méthyl-butyrique, ( R -Fmoc-β-diméthyl-sérine
CAS Number
884880-39-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 215
Molecular Weight
355.39
MDL Number
MFCD02682577
PubChem ID
46737422
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +16 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(R)-Fmoc-b-hydroxy-valine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its protective group allows for selective reactions.
  • Drug Development: It is used in the development of pharmaceuticals, especially in creating peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is valuable in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial for developing biosensors and targeted drug delivery systems.
  • Protein Engineering: It aids in the design of modified proteins with enhanced stability and functionality, which is essential in biotechnology and therapeutic applications.
  • Research in Structural Biology: This chemical is instrumental in studies involving protein structure and function, helping scientists understand molecular interactions and mechanisms.

Citations