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Catalog Number:
29703
CAS Number:
194471-86-8
Acide R , S -Fmoc-3-amino-4,4,4-trifluoro-butyrique
Purity:
≥ 99 % (HPLC)
Documents
$100.05 /25 mg
Taille
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Product Information

(R,S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This amino acid derivative, characterized by its trifluoromethyl group, offers unique properties that enhance the stability and solubility of peptides, making it an essential building block in the development of therapeutic agents. Its Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptide sequences with precision.

Researchers and industry professionals benefit from its application in the design of peptide-based drugs, particularly in the fields of oncology and immunology, where the stability of peptide structures is crucial. Additionally, the trifluoromethyl group imparts distinctive electronic properties that can influence biological activity, making this compound a valuable tool for medicinal chemists aiming to optimize drug efficacy. With its robust profile and practical applications, (R,S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid stands out as a key ingredient in modern peptide chemistry.

CAS Number
194471-86-8
Purity
≥ 99 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NON 4
Molecular Weight
379.34
MDL Number
MFCD02682449
PubChem ID
22661402
Melting Point
203-210 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0-8°C
General Information
CAS Number
194471-86-8
Purity
≥ 99 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NON 4
Molecular Weight
379.34
MDL Number
MFCD02682449
PubChem ID
22661402
Melting Point
203-210 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(R,S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting the overall structure.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of drug candidates, making it valuable in medicinal chemistry for improving bioavailability and metabolic stability.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules like proteins and antibodies to therapeutic agents, which is essential in targeted drug delivery systems.
  • Fluorinated Compounds Research: Researchers utilize it to study the effects of fluorination on biological activity, which can lead to the development of novel fluorinated pharmaceuticals.
  • Analytical Chemistry: It is employed as a standard in analytical methods, helping to calibrate instruments and validate techniques in the quantification of amino acids and peptides.

Citations