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Catalog Number:
28440
CAS Number:
154229-18-2
Acétate d'abiratérone
Purity:
≥ 99%
Documents
$370.25 /1G
Taille
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Informations sur le produit

Abiraterone acetate is a potent and selective inhibitor of androgen biosynthesis, primarily utilized in the treatment of metastatic castration-resistant prostate cancer. This compound works by blocking the enzyme CYP17, which is crucial in the production of androgens, thereby reducing testosterone levels and inhibiting tumor growth. Its effectiveness has made it a cornerstone in prostate cancer therapy, particularly for patients who have not responded to conventional hormone therapies.

In addition to its primary use in oncology, Abiraterone acetate is being explored for potential applications in other hormone-sensitive cancers, showcasing its versatility. Researchers appreciate its ability to improve patient outcomes and prolong survival rates, making it a valuable asset in cancer treatment protocols. The compound's unique mechanism of action sets it apart from other therapies, offering a targeted approach that minimizes side effects while maximizing efficacy.

Numéro CAS 
154229-18-2
Formule moléculaire
C 26 H 332
Poids moléculaire 
391.55
Point de fusion 
144-149 ºC
Informations générales
Numéro CAS 
154229-18-2
Formule moléculaire
C 26 H 332
Poids moléculaire 
391.55
Point de fusion 
144-149 ºC
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
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Applications

Abiraterone acetate is widely utilized in research focused on:

  • Prostate Cancer Treatment: This compound is primarily used in the treatment of metastatic castration-resistant prostate cancer, helping to inhibit tumor growth by blocking androgen production.
  • Hormonal Therapy Research: It serves as a crucial tool in studies exploring hormonal therapies, providing insights into how androgen signaling influences cancer progression.
  • Combination Therapy Studies: Researchers often investigate the efficacy of abiraterone acetate in combination with other cancer treatments, enhancing therapeutic outcomes and understanding drug interactions.
  • Pharmacokinetics and Pharmacodynamics: The compound is used in studies to assess its absorption, distribution, metabolism, and excretion, which are vital for optimizing dosing regimens in clinical settings.
  • Biomarker Identification: Abiraterone acetate is employed in research aimed at identifying biomarkers for treatment response, helping to tailor personalized medicine approaches for patients.

Citations