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Catalog Number:
28435
CAS Number:
33419-42-0
Étoposide
Grade:
USP
Purity:
95 - 105 % (dosage sur une base anhydre)
Documents
$33.65 /250 mg
Taille
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Informations sur le produit

Etoposide is a potent chemotherapeutic agent widely utilized in the treatment of various cancers, including testicular cancer, lung cancer, and certain leukemias. This compound functions primarily as a topoisomerase II inhibitor, disrupting DNA replication and leading to cell death, making it a critical component in cancer therapy regimens. Etoposide's unique structure allows it to effectively penetrate cellular membranes, enhancing its bioavailability and therapeutic efficacy.

In addition to its established role in oncology, Etoposide is also being explored for its potential applications in combination therapies, where it may enhance the effectiveness of other anticancer agents. Researchers appreciate its versatility and the ability to tailor treatment protocols based on individual patient needs. With ongoing studies investigating its use in various malignancies and treatment combinations, Etoposide continues to hold promise as a vital tool in the fight against cancer.

Numéro CAS 
33419-42-0
Formule moléculaire
C 29 H 32 O 13
Poids moléculaire 
588.56
Rotation optique 
[a] D 20 = -110 à -118 º (C = 5 mg/mL dans le chloroforme et le méthanol 9:1)
Informations générales
Numéro CAS 
33419-42-0
Formule moléculaire
C 29 H 32 O 13
Poids moléculaire 
588.56
Rotation optique 
[a] D 20 = -110 à -118 º (C = 5 mg/mL dans le chloroforme et le méthanol 9:1)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Etoposide is widely utilized in research focused on:

  • Cancer Treatment: Etoposide is primarily used as a chemotherapeutic agent for treating various cancers, including testicular cancer and small cell lung cancer. Its effectiveness in disrupting DNA synthesis makes it a critical component in combination therapies.
  • Pharmaceutical Development: In the pharmaceutical industry, etoposide serves as a key compound in the development of new cancer therapies. Researchers are exploring its potential in combination with other drugs to enhance efficacy and reduce side effects.
  • Cell Biology Research: Etoposide is employed in laboratory settings to induce DNA damage in cell cultures, allowing scientists to study cellular responses to DNA damage and repair mechanisms, which is essential for understanding cancer biology.
  • Veterinary Medicine: This compound is also being investigated for its applications in veterinary oncology, providing treatment options for pets diagnosed with certain types of cancer, thus improving their quality of life.
  • Drug Resistance Studies: Etoposide is used in research to study mechanisms of drug resistance in cancer cells, helping to identify new strategies to overcome resistance and improve treatment outcomes for patients.

Citations