Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
27624
CAS Number:
2353-33-5
5-Aza-2'-désoxycytidine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Décitabine, 2'-désoxy-5-azacytidine
Documents
$58.39 /100 mg
Taille
Request Bulk Quote
Product Information

2'-Deoxy-5-azacytidine is a nucleoside analog that has garnered significant attention in the fields of molecular biology and pharmacology. This compound is particularly notable for its role as a potential therapeutic agent in cancer treatment and epigenetic research. By incorporating into DNA, 2'-Deoxy-5-azacytidine can inhibit DNA methyltransferases, leading to the demethylation of genes that are silenced in various cancers. This unique property makes it an invaluable tool for researchers aiming to understand gene regulation and for developing novel cancer therapies.

In addition to its applications in oncology, 2'-Deoxy-5-azacytidine is also utilized in the study of epigenetic modifications and their impact on cellular processes. Its ability to modulate gene expression provides insights into developmental biology and disease mechanisms. Researchers and industry professionals can leverage this compound to explore innovative solutions in gene therapy and regenerative medicine, making it a versatile addition to any laboratory focused on cutting-edge biomedical research.

Synonyms
Décitabine, 2'-désoxy-5-azacytidine
CAS Number
2353-33-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C8H12N4O4
Molecular Weight
228.21
MDL Number
MFCD00043011
PubChem ID
16886
Appearance
Poudre cristalline blanche à blanc cassé
Optical Rotation
[a] D 20 = 66-76º
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Décitabine, 2'-désoxy-5-azacytidine
CAS Number
2353-33-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C8H12N4O4
Molecular Weight
228.21
MDL Number
MFCD00043011
PubChem ID
16886
Appearance
Poudre cristalline blanche à blanc cassé
Optical Rotation
[a] D 20 = 66-76º
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

2'-Deoxy-5-azacytidine is widely utilized in research focused on:

  • Cancer Treatment: This compound is being explored as a potential therapeutic agent in oncology. It has shown promise in inhibiting tumor growth by affecting DNA methylation, which is crucial in cancer progression.
  • Epigenetic Research: Researchers use it to study epigenetic modifications. Its ability to mimic cytidine allows scientists to investigate the role of DNA methylation in gene expression and cellular differentiation.
  • Antiviral Applications: The compound is being investigated for its antiviral properties, particularly against certain viruses. Its mechanism can interfere with viral replication, making it a candidate for developing antiviral therapies.
  • Cellular Reprogramming: In stem cell research, it is used to enhance the reprogramming efficiency of somatic cells into induced pluripotent stem cells (iPSCs), which is vital for regenerative medicine.
  • Drug Development: Pharmaceutical companies are exploring its potential as a lead compound for developing new drugs targeting various diseases, leveraging its unique chemical structure for improved efficacy.

Citations