Découvrez le nouveau Chem-Impex : là où l'innovation commence par une liaison.

Catalog Number:
24174
CAS Number:
30562-34-6
Geldanamycine issue de Streptomyces hygroscopicus
Purity:
≥ 99 % (HPLC)
Documents
$60.00 /25 mg
Taille
Request Bulk Quote
Informations sur le produit

Geldanamycin is a potent ansamycin antibiotic derived from the bacterium Streptomyces hygroscopicus, renowned for its ability to inhibit heat shock protein 90 (Hsp90). This unique mechanism of action makes Geldanamycin a valuable compound in cancer research and treatment, as it disrupts the function of several client proteins involved in tumor growth and survival. Researchers have utilized Geldanamycin in various studies to explore its efficacy against a range of cancers, including breast, prostate, and lung cancer, showcasing its potential as a therapeutic agent.

In addition to its applications in oncology, Geldanamycin has garnered interest in the field of neurodegenerative diseases due to its neuroprotective properties. Its ability to modulate protein folding and degradation pathways presents opportunities for developing treatments for conditions such as Alzheimer's and Parkinson's disease. With its diverse applications and ongoing research, Geldanamycin stands out as a compound of significant interest for both academic and industrial professionals seeking innovative solutions in drug development.

Numéro CAS 
30562-34-6
Formule moléculaire
C29H40N2O9
Poids moléculaire 
560.64
Point de fusion 
259 - 261 °C
Informations générales
Numéro CAS 
30562-34-6
Formule moléculaire
C29H40N2O9
Poids moléculaire 
560.64
Point de fusion 
259 - 261 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
-
Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
-
Applications

Geldanamycin is widely utilized in research focused on

  • Cancer Treatment: This compound is known for its ability to inhibit heat shock protein 90 (HSP90), which is crucial for the stability of many oncogenic proteins. Researchers are exploring its potential as a targeted therapy in various cancer types.
  • Drug Development: Geldanamycin serves as a lead compound in the development of novel anticancer drugs. Its unique mechanism of action provides a foundation for creating more effective therapies with fewer side effects.
  • Biotechnology: In the field of biotechnology, it is used to study protein folding and degradation processes, helping scientists understand cellular stress responses and develop strategies to combat diseases related to protein misfolding.
  • Neurodegenerative Disease Research: The compound is being investigated for its potential benefits in treating neurodegenerative diseases, as it may help in the stabilization of proteins involved in these conditions.
  • Combination Therapies: Geldanamycin is often used in combination with other therapeutic agents to enhance the efficacy of treatment regimens, particularly in overcoming drug resistance in cancer therapies.

Citations