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Catalog Number:
22679
CAS Number:
502640-94-0
Fmoc-L-Asp(OtBu)-HmbGly-OH
Purity:
≥ 96 % (HPLC)
Synonym(s):
Fmoc-Asp(OtBu)- N -(2-hydroxy-4-méthoxy-bzl)-Gly-OH
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$86.23 /100 mg
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Product Information

Fmoc-L-Asp(OtBu)-HmbGly-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc group, which is essential for the selective deprotection of amino acids during solid-phase peptide synthesis (SPPS). Its unique structure, incorporating a tert-butyl ester and a hydroxyphenyl moiety, enhances its stability and solubility, making it an excellent choice for researchers focused on synthesizing complex peptides and proteins.

In the pharmaceutical industry, Fmoc-L-Asp(OtBu)-HmbGly-OH serves as a crucial building block for the development of therapeutics targeting various diseases, including cancer and neurodegenerative disorders. Its ability to facilitate the incorporation of aspartic acid into peptide sequences allows for the design of bioactive compounds with improved efficacy and specificity. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in generating high-purity products, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-Asp(OtBu)- N -(2-hydroxy-4-méthoxy-bzl)-Gly-OH
CAS Number
502640-94-0
Purity
≥ 96 % (HPLC)
Molecular Formula
C33H36N2O9
Molecular Weight
604.66
MDL Number
MFCD06656487
PubChem ID
4712616
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -24 ± 2º (C = 1 dans THF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-Asp(OtBu)- N -(2-hydroxy-4-méthoxy-bzl)-Gly-OH
CAS Number
502640-94-0
Purity
≥ 96 % (HPLC)
Molecular Formula
C33H36N2O9
Molecular Weight
604.66
MDL Number
MFCD06656487
PubChem ID
4712616
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -24 ± 2º (C = 1 dans THF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-Asp(OtBu)-HmbGly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences with high purity and yield.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly for targeting specific biological pathways, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound can be used to create bioconjugates, which are essential in developing targeted therapies and diagnostic tools, enhancing the specificity of drug delivery systems.
  • Research in Neuroscience: It is utilized in the study of neurotransmitter systems, particularly in the development of compounds that can modulate synaptic activity, aiding in the understanding of neurological disorders.
  • Protein Engineering: Fmoc-L-Asp(OtBu)-HmbGly-OH is important in the modification of proteins, allowing scientists to introduce specific functionalities that can improve protein stability and activity in various applications.

Citations