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Catalog Number:
22674
CAS Number:
281655-34-3
(2S,4R)-Fmoc-Mpt(Trt)-OH
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide (2S,4R)-Fmoc-4-tritylmercapto-pyrrolidine-2-carboxylique
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$125.00 /25 mg
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Product Information

The compound (2S,4R)-Fmoc-Mpt(Trt)-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique structure that includes a fluorenylmethoxycarbonyl (Fmoc) protecting group and a trityl (Trt) sulfanyl group, making it particularly valuable for the synthesis of complex peptides. Its chiral centers contribute to the specificity required in pharmaceutical applications, allowing researchers to create compounds with precise stereochemistry.

In the field of medicinal chemistry, (2S,4R)-Fmoc-Mpt(Trt)-OH is instrumental in the development of peptide-based therapeutics, where its stability and reactivity facilitate the formation of peptide bonds under mild conditions. This compound is also advantageous in solid-phase peptide synthesis, where it enhances the efficiency of coupling reactions. Researchers appreciate its ability to provide high yields and purity in the final products, making it a preferred choice for those working on innovative drug formulations and bioconjugates.

Synonyms
Acide (2S,4R)-Fmoc-4-tritylmercapto-pyrrolidine-2-carboxylique
CAS Number
281655-34-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 23 NON 2 S
Molecular Weight
611.75
MDL Number
MFCD01860721
PubChem ID
53395530
Melting Point
170 - 178 °C (lit.)
Appearance
Poudre/solide blanche
Optical Rotation
[a] D 20 = 25 ± 2 º (C = 1 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Acide (2S,4R)-Fmoc-4-tritylmercapto-pyrrolidine-2-carboxylique
CAS Number
281655-34-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 23 NON 2 S
Molecular Weight
611.75
MDL Number
MFCD01860721
PubChem ID
53395530
Melting Point
170 - 178 °C (lit.)
Appearance
Poudre/solide blanche
Optical Rotation
[a] D 20 = 25 ± 2 º (C = 1 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(2S,4R)-Fmoc-Mpt(Trt)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development and biological studies.
  • Drug Discovery: Its unique properties facilitate the design of novel pharmaceuticals, particularly in targeting specific biological pathways, enhancing the efficiency of drug candidates.
  • Bioconjugation: The compound is used in bioconjugation processes, helping to attach drugs or imaging agents to proteins, which is essential in targeted therapy and diagnostics.
  • Research in Neuroscience: It plays a role in studying neuropeptides, contributing to our understanding of neurological functions and potential treatments for disorders.
  • Custom Synthesis Services: Many chemical suppliers offer tailored synthesis of this compound, providing researchers with the flexibility to obtain specific derivatives for their unique applications.

Citations