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Catalog Number:
22163
CAS Number:
73573-88-3
Mévastatine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Compactine, ML-236B
Antibiotic
Documents
$58.39 /250 mg
Taille
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Informations sur le produit

Mevastatin is a potent statin compound recognized for its role in cholesterol management and cardiovascular health. As a competitive inhibitor of HMG-CoA reductase, it effectively reduces low-density lipoprotein (LDL) cholesterol levels, making it a valuable asset in the treatment of hyperlipidemia. This compound has been extensively studied for its ability to lower cholesterol, thereby potentially reducing the risk of heart disease and stroke. Researchers and healthcare professionals appreciate Mevastatin for its efficacy in lipid regulation, and it serves as a foundational compound in the development of various cholesterol-lowering therapies.

In addition to its primary use in managing cholesterol levels, Mevastatin has shown promise in various research applications, including studies on metabolic syndrome and inflammation. Its unique structure allows for modifications that can enhance its therapeutic profile, making it a subject of interest in pharmaceutical development. Mevastatin's established safety profile and effectiveness in clinical settings further underscore its relevance in both research and therapeutic applications, providing a reliable option for professionals seeking to address lipid-related health issues.

Numéro CAS 
73573-88-3
Formule moléculaire
C23H34O5
Poids moléculaire 
390.51
Point de fusion 
151-155 °C
Rotation optique 
[a] D 20 = +280 à +295° (C=0,48 dans l'acétone)
Informations générales
Numéro CAS 
73573-88-3
Formule moléculaire
C23H34O5
Poids moléculaire 
390.51
Point de fusion 
151-155 °C
Rotation optique 
[a] D 20 = +280 à +295° (C=0,48 dans l'acétone)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Mevastatin is widely utilized in research focused on:

  • Cholesterol Management: As a statin, it effectively lowers cholesterol levels, making it valuable in the treatment of hyperlipidemia and cardiovascular diseases.
  • Pharmaceutical Development: It serves as a model compound for developing new cholesterol-lowering medications, aiding researchers in understanding statin mechanisms and improving drug efficacy.
  • Biochemical Research: Mevastatin is used to study the effects of cholesterol synthesis inhibition on cellular processes, providing insights into metabolic pathways and disease mechanisms.
  • Clinical Trials: It plays a crucial role in clinical studies assessing the long-term effects of statin therapy on heart health, helping to establish guidelines for patient care.
  • Comparative Studies: Researchers utilize it to compare the effectiveness and safety of newer statins, contributing to informed decisions in prescribing practices.

Citations