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Catalog Number:
21917
CAS Number:
51-20-7
5-Bromouracile
Purity:
≥ 99 % (HPLC)
Synonym(s):
5-Bromo-1 H -pyrimidine-2,4-dione, 5-Bromo-2,3-dihydroxypyrimidine
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Product Information

5-Bromouracil is a halogenated derivative of uracil, recognized for its significant role in molecular biology and medicinal chemistry. This compound serves as a potent antimetabolite, primarily utilized in cancer research and treatment. Its ability to mimic the structure of nucleobases allows it to interfere with DNA synthesis, making it a valuable tool in the development of chemotherapeutic agents. Researchers have effectively employed 5-Bromouracil in studies related to mutagenesis and the mechanisms of DNA repair, showcasing its importance in understanding genetic mutations and their implications in cancer progression.

In addition to its applications in cancer research, 5-Bromouracil is also utilized in the synthesis of various pharmaceuticals and biochemicals. Its unique properties enable it to act as a selective inhibitor in enzymatic reactions, providing a pathway for the development of targeted therapies. The compound's versatility and effectiveness in disrupting cellular processes make it an essential reagent for professionals in the fields of biochemistry and molecular biology, offering insights into cellular mechanisms and potential therapeutic strategies.

Synonyms
5-Bromo-1 H -pyrimidine-2,4-dione, 5-Bromo-2,3-dihydroxypyrimidine
CAS Number
51-20-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H3BrN2O2
Molecular Weight
190.98
MDL Number
MFCD00006017
PubChem ID
5802
Appearance
Poudre blanche à jaune clair
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
5-Bromo-1 H -pyrimidine-2,4-dione, 5-Bromo-2,3-dihydroxypyrimidine
CAS Number
51-20-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H3BrN2O2
Molecular Weight
190.98
MDL Number
MFCD00006017
PubChem ID
5802
Appearance
Poudre blanche à jaune clair
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

5-Bromouracil is widely utilized in research focused on:

  • Antiviral Research: This compound is used in the development of antiviral drugs, particularly against herpes simplex virus, due to its ability to interfere with viral DNA synthesis.
  • Cancer Research: It serves as a tool in cancer studies, specifically in understanding the mechanisms of tumor growth and the effects of brominated pyrimidines on DNA replication.
  • Genetic Studies: Researchers employ 5-Bromouracil to induce mutations in microbial and plant systems, aiding in the study of genetic variability and evolution.
  • Pharmaceutical Development: The compound is explored in the synthesis of new drugs, offering a unique structure that can enhance the efficacy of certain medications compared to traditional compounds.
  • Biochemical Assays: It is used in various assays to evaluate the effects of nucleoside analogs on cellular processes, providing insights into cellular metabolism and drug interactions.

Citations