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Catalog Number:
16862
CAS Number:
266999-24-0
Fmoc-3-(Boc-aminométhyl)-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Phe(3-CH2NHBoc)-OH, Fmoc- m -(Boc-aminométhyl)-L-Phe-OH, Fmoc-Phe(3-CH2NHBoc)-OH
Documents
$85.00 /250 mg
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Product Information

Fmoc-3-(Boc-aminomethyl)-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. The Boc (tert-butoxycarbonyl) group further enhances its stability and compatibility in various chemical reactions, making it an ideal choice for researchers focused on synthesizing complex peptides and proteins.

In practical applications, this compound is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics. Its unique structure allows for efficient coupling reactions, facilitating the creation of diverse peptide sequences. Researchers appreciate its ability to improve yields and simplify purification processes, ultimately accelerating the development of new drugs. Additionally, Fmoc-3-(Boc-aminomethyl)-L-phenylalanine's compatibility with automated synthesizers enhances its appeal for high-throughput screening in drug discovery.

Synonyms
Fmoc-L-Phe(3-CH2NHBoc)-OH, Fmoc- m -(Boc-aminométhyl)-L-Phe-OH, Fmoc-Phe(3-CH2NHBoc)-OH
CAS Number
266999-24-0
Purity
≥ 98 % (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD01860734
PubChem ID
53398428
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -26 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3-CH2NHBoc)-OH, Fmoc- m -(Boc-aminométhyl)-L-Phe-OH, Fmoc-Phe(3-CH2NHBoc)-OH
CAS Number
266999-24-0
Purity
≥ 98 % (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD01860734
PubChem ID
53398428
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -26 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3-(Boc-aminomethyl)-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, facilitating the incorporation of phenylalanine into various peptide sequences. Its protective groups allow for selective reactions, enhancing the efficiency of synthesis.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. Its ability to modify peptide structures can lead to improved bioavailability and targeted delivery of therapeutic agents.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it helps attach peptides to other biomolecules, such as antibodies or enzymes, improving their functionality and stability in therapeutic applications.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, aiding researchers in understanding the role of specific peptides in neurological functions and disorders, which can lead to new treatment strategies.
  • Custom Peptide Libraries: The compound is instrumental in generating custom peptide libraries for high-throughput screening, allowing researchers to explore a wide range of peptide interactions and functionalities in drug discovery.

Citations