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Catalog Number:
15720
CAS Number:
1217741-88-2
Acide Fmoc-( S -3-amino-3-(2-furyl)propionique)
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-β-Ala-(2-furyl)-OH
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$86.23 /100 mg
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Product Information

Fmoc-(S)-3-amino-3-(2-furyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique furan moiety, which enhances its reactivity and provides opportunities for the development of novel therapeutic agents. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while maintaining stability during synthesis. Researchers appreciate its application in the design of bioactive peptides, particularly in the fields of drug discovery and development, where the ability to modify peptide sequences can lead to improved efficacy and selectivity.

The compound's specific structure enables it to participate in various coupling reactions, making it an essential tool for chemists aiming to create complex peptide architectures. Its compatibility with standard coupling reagents and methodologies streamlines the synthesis process, saving time and resources. Additionally, the unique properties of Fmoc-(S)-3-amino-3-(2-furyl)propionic acid position it as a valuable asset in the exploration of new therapeutic pathways, particularly in oncology and neurobiology, where peptide-based drugs are gaining traction.

Synonyms
Fmoc-D-β-Ala-(2-furyl)-OH
CAS Number
1217741-88-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C 22 H 195
Molecular Weight
377.4
MDL Number
MFCD04117841
PubChem ID
53398097
Melting Point
177-182 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -51 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-D-β-Ala-(2-furyl)-OH
CAS Number
1217741-88-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C 22 H 195
Molecular Weight
377.4
MDL Number
MFCD04117841
PubChem ID
53398097
Melting Point
177-182 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -51 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(2-furyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its protective Fmoc group allows for selective deprotection and coupling.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, especially those targeting neurological disorders, due to the furan moiety's potential biological activity.
  • Bioconjugation: Researchers leverage this compound for bioconjugation applications, linking peptides to various biomolecules for targeted drug delivery systems, enhancing therapeutic efficacy.
  • Material Science: The compound is explored in the development of functional materials, including hydrogels and nanomaterials, which can be used in drug delivery and tissue engineering.
  • Analytical Chemistry: It is used as a standard in analytical methods, aiding in the quantification of amino acids and peptides in complex biological samples, ensuring accuracy in research findings.

Citations