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Catalog Number:
15542
CAS Number:
507472-13-1
Acide Fmoc-( S )-3-amino-3-(2-fluorophényl)propionique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-β-Phe(2-F)-OH, ( S )-Fmoc-2-fluoro-β-phénylalanine
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Product Information

Fmoc-(S)-3-amino-3-(2-fluorophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorinated aromatic group, enhancing its potential for biological activity and selectivity in drug design. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Researchers appreciate its application in the development of peptide-based therapeutics, particularly in targeting specific receptors or enzymes due to the unique properties imparted by the fluorine atom.

In addition to its role in peptide synthesis, this compound can be employed in the creation of novel materials and ligands in various fields, including pharmaceuticals and biochemistry. Its ability to facilitate the introduction of fluorine into molecular structures opens pathways for the development of compounds with improved pharmacokinetic profiles. With its combination of stability, reactivity, and biological relevance, Fmoc-(S)-3-amino-3-(2-fluorophenyl)propionic acid is an essential tool for researchers aiming to innovate in drug discovery and development.

Synonyms
Fmoc-L-β-Phe(2-F)-OH, ( S )-Fmoc-2-fluoro-β-phénylalanine
CAS Number
507472-13-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.42
MDL Number
MFCD03427993
PubChem ID
2759192
Melting Point
177 - 178 ?C
Appearance
Solide blanc
Optical Rotation
[a] D 20 = -22,9 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Phe(2-F)-OH, ( S )-Fmoc-2-fluoro-β-phénylalanine
CAS Number
507472-13-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.42
MDL Number
MFCD03427993
PubChem ID
2759192
Melting Point
177 - 178 ?C
Appearance
Solide blanc
Optical Rotation
[a] D 20 = -22,9 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(2-fluorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: Its unique fluorinated phenyl group enhances the pharmacological properties of peptides, making it valuable in the pharmaceutical industry for developing new therapeutic agents.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of peptides to various biomolecules, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: This chemical is employed in studies related to neurotransmitter systems, helping researchers understand the role of specific amino acids in brain function and potential treatments for neurological disorders.
  • Analytical Chemistry: It is used as a standard in analytical methods, aiding in the characterization and quantification of peptides in various biological samples, which is essential for quality control in research and clinical settings.

Citations