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Catalog Number:
15102
CAS Number:
273221-78-6
Boc-2-iodo-L-phénylalanine
Purity:
≥ 99 % (HPLC chirale)
Synonym(s):
Boc-L-Phe(2-I)-OH, Boc- o -iodo-L-Phe-OH, Acide (S)-Boc-2-amino-3-(2-iodophényl)propionique
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Product Information

Boc-2-iodo-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal building block for the development of complex peptides and proteins. Its unique structure, characterized by the presence of an iodine atom, allows for specific labeling and functionalization in various biochemical applications. Researchers often leverage Boc-2-iodo-L-phenylalanine in the synthesis of peptide-based therapeutics, where it can facilitate the introduction of iodine for imaging or targeting purposes.

In addition to its role in peptide synthesis, Boc-2-iodo-L-phenylalanine is valuable in the study of protein interactions and enzyme mechanisms. Its ability to participate in various coupling reactions expands its utility in the development of novel biomolecules. This compound stands out for its ease of handling and compatibility with standard laboratory protocols, making it a preferred choice for both academic and industrial researchers seeking to innovate in the fields of drug discovery and biochemistry.

Synonyms
Boc-L-Phe(2-I)-OH, Boc- o -iodo-L-Phe-OH, Acide (S)-Boc-2-amino-3-(2-iodophényl)propionique
CAS Number
273221-78-6
Purity
≥ 99 % (HPLC chirale)
Molecular Formula
C 14 H 18 INO 4
Molecular Weight
391.2
MDL Number
MFCD01860645
PubChem ID
53395431
Melting Point
157 - 163 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -40 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Boc-L-Phe(2-I)-OH, Boc- o -iodo-L-Phe-OH, Acide (S)-Boc-2-amino-3-(2-iodophényl)propionique
CAS Number
273221-78-6
Purity
≥ 99 % (HPLC chirale)
Molecular Formula
C 14 H 18 INO 4
Molecular Weight
391.2
MDL Number
MFCD01860645
PubChem ID
53395431
Melting Point
157 - 163 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -40 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-2-iodo-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the creation of modified peptides that can exhibit enhanced biological activity.
  • Drug Development: Its unique structure allows researchers to explore new therapeutic agents, especially in the fields of cancer and neurological disorders, by incorporating it into potential drug candidates.
  • Bioconjugation: The iodine atom in the compound can facilitate bioconjugation processes, making it useful for labeling biomolecules in imaging and diagnostic applications.
  • Research in Protein Engineering: It is employed in the modification of proteins to study structure-function relationships, helping scientists understand how changes at the molecular level can affect protein behavior.
  • Development of Novel Therapeutics: The compound's ability to mimic natural amino acids while introducing unique properties makes it valuable in designing novel therapeutics that can target specific biological pathways.

Citations