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Catalog Number:
14864
CAS Number:
152338-45-9
N α - Fmoc- N in -formyl-L-tryptophane
Purity:
≥ 99 % (HPLC, CCM)
Synonym(s):
Fmoc-L-Trp(For)-OH
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Informations sur le produit

Na-Fmoc-Nin-formyl-L-tryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis. Its unique structure, combining the indole moiety of tryptophan with a formyl group, enhances its reactivity and allows for the introduction of various functional groups, making it an essential building block in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its stability under standard synthesis conditions, which contributes to higher yields and purity in peptide production.

In addition to its role in peptide synthesis, Na-Fmoc-Nin-formyl-L-tryptophan has potential applications in the development of targeted therapies and drug delivery systems. Its ability to form stable conjugates with other biomolecules opens avenues for creating innovative therapeutic agents. This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where the precise control of molecular structure is crucial for the efficacy of therapeutic compounds. With its robust performance and adaptability, Na-Fmoc-Nin-formyl-L-tryptophan stands out as a key ingredient for researchers and industry professionals focused on advancing peptide-based technologies.

Numéro CAS 
152338-45-9
Formule moléculaire
C27H22N2O5
Poids moléculaire 
454.48
Point de fusion 
188 - 193 °C
Rotation optique 
[a] D 20 = -23 ± 2 ° (C = 1 dans DMF)
Informations générales
Numéro CAS 
152338-45-9
Formule moléculaire
C27H22N2O5
Poids moléculaire 
454.48
Point de fusion 
188 - 193 °C
Rotation optique 
[a] D 20 = -23 ± 2 ° (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Na-Fmoc-Nin-formyl-L-tryptophan is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It is used in the design of novel pharmaceuticals, especially those targeting neurological disorders, due to its structural similarity to neurotransmitters, facilitating the development of effective drug candidates.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, enabling researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Fluorescent Probes: Its unique structure allows it to be used in the development of fluorescent probes for imaging applications in biological research, enhancing the visualization of cellular processes.
  • Research in Tryptophan Metabolism: This compound aids in studies related to tryptophan metabolism, helping researchers understand its role in various biological processes and its implications in health and disease.

Citations