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Catalog Number:
12794
CAS Number:
114873-12-0
Boc-2,4-dichloro-D-phénylalanine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Boc-D-Phe(2,4-DiCl)-OH, Boc-D-Phe(2,4- Cl2 )-OH
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Product Information

Boc-2,4-dichloro-D-phenylalanine is a versatile amino acid derivative that plays a significant role in peptide synthesis and pharmaceutical development. This compound is recognized for its unique ability to introduce chlorinated aromatic functionalities into peptides, enhancing their biological activity and stability. Its protective Boc (tert-butyloxycarbonyl) group allows for selective deprotection during synthesis, making it an ideal choice for researchers focused on developing novel therapeutic agents.

In the pharmaceutical industry, Boc-2,4-dichloro-D-phenylalanine is utilized in the design of peptide-based drugs, particularly in the development of inhibitors and modulators for various biological targets. Its application extends to the synthesis of biologically active compounds, where the incorporation of the dichlorophenyl moiety can significantly influence the pharmacological properties of the resulting peptides. This compound's ability to facilitate complex peptide synthesis while maintaining high purity and yield makes it an invaluable tool for chemists and researchers in drug discovery and development.

Synonyms
Boc-D-Phe(2,4-DiCl)-OH, Boc-D-Phe(2,4- Cl2 )-OH
CAS Number
114873-12-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD01862941
PubChem ID
4393347
Melting Point
132-136 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D = +32,5 ± 2° (c = 1 % MeOH)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Boc-D-Phe(2,4-DiCl)-OH, Boc-D-Phe(2,4- Cl2 )-OH
CAS Number
114873-12-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD01862941
PubChem ID
4393347
Melting Point
132-136 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D = +32,5 ± 2° (c = 1 % MeOH)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-2,4-dichloro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of therapeutic agents. Its unique structure allows for the incorporation of specific functionalities that enhance biological activity.
  • Drug Development: Researchers leverage its properties to create novel drug candidates, especially in the field of cancer research, where modifications can lead to more effective treatments with reduced side effects.
  • Biochemical Studies: It is used in studies investigating protein interactions and enzyme mechanisms, providing insights into how modifications can affect biological functions.
  • Analytical Chemistry: The compound is employed in various analytical techniques, including chromatography, to separate and identify complex mixtures, aiding in quality control in pharmaceutical manufacturing.
  • Material Science: Its unique chemical properties make it suitable for the development of specialized materials, including those used in drug delivery systems, enhancing the efficacy and targeting of therapeutic agents.

Citations