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Catalog Number:
12771
CAS Number:
193954-27-7
Fmoc-L-β-homoisoleucine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-β-HomoIle-OH, (3 R ,4 S -acide 3-(Fmoc-amino)-4-méthylhexanoïque
Documents
$93.14 /250 mg
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Product Information

Fmoc-L-b-homoisoleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an excellent choice for solid-phase peptide synthesis. Researchers appreciate its unique structure, which includes a branched chain that provides distinct steric properties, allowing for the creation of peptides with enhanced biological activity and specificity.

In the pharmaceutical industry, Fmoc-L-b-homoisoleucine is particularly valuable for the development of peptide-based therapeutics, where its incorporation can lead to improved binding affinity and selectivity for target receptors. Additionally, its application extends to the synthesis of cyclic peptides and other complex structures, showcasing its flexibility in various research settings. With its reliable performance and ability to facilitate the design of innovative compounds, Fmoc-L-b-homoisoleucine stands out as a crucial building block for researchers and industry professionals alike.

Synonyms
Fmoc-L-β-HomoIle-OH, (3 R ,4 S -acide 3-(Fmoc-amino)-4-méthylhexanoïque
CAS Number
193954-27-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 22 H 254
Molecular Weight
367.45
MDL Number
MFCD01862850
PubChem ID
5102880
Melting Point
130 - 132 °C (déc.)
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -24 ± 1 º (C = 0,5 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoIle-OH, (3 R ,4 S -acide 3-(Fmoc-amino)-4-méthylhexanoïque
CAS Number
193954-27-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 22 H 254
Molecular Weight
367.45
MDL Number
MFCD01862850
PubChem ID
5102880
Melting Point
130 - 132 °C (déc.)
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -24 ± 1 º (C = 0,5 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-b-homoisoleucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of unique amino acid sequences.
  • Drug Development: It plays a significant role in the development of peptide-based drugs, providing researchers with the ability to create more effective and targeted therapeutic agents.
  • Bioconjugation: Fmoc-L-b-homoisoleucine can be used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Protein Engineering: This compound is valuable in protein engineering, allowing scientists to modify protein structures to enhance stability and functionality, which is essential in various biotechnological applications.
  • Research in Structural Biology: It aids in the study of protein structures and interactions, providing insights that are vital for understanding biological processes and developing new biopharmaceuticals.

Citations