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Catalog Number:
12395
CAS Number:
174080-12-7
Ester de N α - Fmoc-D-tryptophane N -hydroxysuccinimide
Purity:
≥ 97 % (HPLC)
Synonym(s):
Fmoc-D-Trp-OSu
Documents
$67.60 /1G
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Informations sur le produit

Na-Fmoc-D-tryptophan N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the field of medicinal chemistry. Its unique structure enhances the stability and solubility of peptides, facilitating the development of complex biomolecules.

This compound is particularly valuable in the synthesis of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Researchers can leverage its properties to create targeted drug delivery systems or to explore novel therapeutic pathways. Additionally, Na-Fmoc-D-tryptophan N-hydroxysuccinimide ester can be employed in the study of protein interactions and enzyme activities, providing insights that are vital for advancing biochemistry and pharmacology. Its ability to streamline peptide synthesis while maintaining high purity levels makes it a preferred choice among professionals in the industry.

Numéro CAS 
174080-12-7
Formule moléculaire
C30H25N3O6
Poids moléculaire 
523.5
Point de fusion 
103-107 °C (déc.)
Rotation optique 
[α] D 20 = +22 ± 2º (C=1% dans Dioxane)
Informations générales
Numéro CAS 
174080-12-7
Formule moléculaire
C30H25N3O6
Poids moléculaire 
523.5
Point de fusion 
103-107 °C (déc.)
Rotation optique 
[α] D 20 = +22 ± 2º (C=1% dans Dioxane)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Na-Fmoc-D-tryptophan N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly for creating complex sequences that include D-tryptophan. Its use enhances the efficiency of solid-phase peptide synthesis, allowing for the production of high-purity peptides.
  • Drug Development: In pharmaceutical research, it is employed to develop novel drug candidates that target specific biological pathways. Its ability to modify the structure of peptides can lead to improved pharmacokinetic properties.
  • Bioconjugation: The N-hydroxysuccinimide ester functionality allows for easy conjugation with various biomolecules, facilitating the creation of targeted drug delivery systems and diagnostic agents in biomedicine.
  • Research in Neuroscience: This compound is used in studies related to neurotransmitter pathways, particularly those involving tryptophan derivatives, which are crucial for understanding mood regulation and mental health.
  • Protein Engineering: It plays a role in modifying proteins to enhance their stability and activity, making it valuable in the development of enzyme inhibitors and therapeutic proteins.

Citations