Découvrez le nouveau Chem-Impex : là où l'innovation commence par une liaison.

Catalog Number:
07392
CAS Number:
247113-86-6
Fmoc- p -trifluorométhyl-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Phe(4-CF3)-OH, Fmoc-Phe(4-trifluorométhyl)-OH
Documents
$80.50 /1G
Taille
Request Bulk Quote
Informations sur le produit

Fmoc-p-trifluoromethyl-L-phenylalanine is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to enhance the stability and bioactivity of peptides. The trifluoromethyl group not only contributes to the compound's unique properties but also improves lipophilicity, making it an excellent candidate for pharmaceutical applications. Researchers utilize Fmoc-p-trifluoromethyl-L-phenylalanine in the synthesis of peptide-based therapeutics, where its protective Fmoc group allows for selective deprotection during the synthesis process, facilitating the creation of complex peptide structures.

In addition to its applications in drug discovery, this compound is also employed in the development of novel materials and bioconjugates. Its unique chemical properties enable the design of peptides with enhanced binding affinities and improved pharmacokinetic profiles. Fmoc-p-trifluoromethyl-L-phenylalanine stands out among similar compounds due to its trifluoromethyl substitution, which can significantly influence the biological activity of the resulting peptides. This makes it an invaluable tool for researchers aiming to develop innovative solutions in the pharmaceutical and biotechnology sectors.

Numéro CAS 
247113-86-6
Formule moléculaire
C 25 H 20 F 3 NON 4
Poids moléculaire 
455.43
Point de fusion 
120 - 140 °C
Rotation optique 
[a]D20 = -37 ± 2 ° (C=1 dans DMF)
Informations générales
Numéro CAS 
247113-86-6
Formule moléculaire
C 25 H 20 F 3 NON 4
Poids moléculaire 
455.43
Point de fusion 
120 - 140 °C
Rotation optique 
[a]D20 = -37 ± 2 ° (C=1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
-
Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
-
Applications

Fmoc-p-trifluoromethyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity and yield.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of peptides, making it valuable in the development of novel therapeutics with improved efficacy and stability.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach peptides to various biomolecules, facilitating targeted drug delivery systems and improving the specificity of therapeutic agents.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of structure-function relationships and the development of proteins with enhanced functionalities.
  • Fluorinated Compound Studies: Its incorporation into molecular structures allows scientists to explore the effects of fluorination on biological activity, providing insights into the design of new compounds with desired properties.

Citations