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Catalog Number:
07110
CAS Number:
682800-84-6
Fmoc- O -trityl-D-thréonine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Thr(Trt)-OH
Documents
$65.40 /1G
Taille
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Informations sur le produit

La chaîne latérale peut être déprotégée de manière sélective sur la phase solide avec 1 % de TFA/5 % de triisopropylsilane.

Numéro CAS 
682800-84-6
Formule moléculaire
C 38 H 335
Poids moléculaire 
583.7
Point de fusion 
70-75 °C
Rotation optique 
[a] D 20 = +25,5 ± 2º (C = 1 dans EtOAc)
Informations générales
Numéro CAS 
682800-84-6
Formule moléculaire
C 38 H 335
Poids moléculaire 
583.7
Point de fusion 
70-75 °C
Rotation optique 
[a] D 20 = +25,5 ± 2º (C = 1 dans EtOAc)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-O-trityl-D-threonine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. This is particularly useful in the pharmaceutical industry for developing new drugs.
  • Bioconjugation: It is employed in bioconjugation techniques to attach biomolecules, such as proteins or nucleic acids, to surfaces or other molecules. This application is vital in the development of targeted therapies and diagnostics.
  • Research in Protein Engineering: Researchers use this compound to study protein folding and stability, which can lead to advancements in enzyme design and therapeutic proteins, enhancing drug efficacy.
  • Development of Antibody-Drug Conjugates: Fmoc-O-trityl-D-threonine is instrumental in creating antibody-drug conjugates, which are designed to deliver cytotoxic drugs directly to cancer cells, minimizing damage to healthy tissue.
  • Custom Synthesis Services: Companies specializing in custom peptide synthesis utilize this compound to provide tailored solutions for clients in academia and industry, ensuring high-quality and specific peptide sequences for research and therapeutic purposes.

Citations