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Catalog Number:
07056
CAS Number:
195434-42-5
Fmoc-3,5-dinitro-L-tyrosine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-3,5-dinitro-L-Tyr-OH, Fmoc-3,5-dinitro-4-hydroxy-L-phénylalanine
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$132.20 /250 mg
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Product Information

Fmoc-3,5-dinitro-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by the presence of dinitrophenyl groups, enhances its reactivity and allows for the introduction of nitro functionalities, making it an excellent choice for researchers focused on developing novel therapeutics and biomolecules.

In addition to its role in peptide synthesis, Fmoc-3,5-dinitro-L-tyrosine serves as a valuable building block in the design of targeted drug delivery systems and molecular probes. Its ability to participate in various chemical reactions opens up possibilities for creating complex molecules with specific biological activities. Researchers in medicinal chemistry and biochemistry will find this compound particularly beneficial for exploring structure-activity relationships and optimizing lead compounds for pharmaceutical applications.

Synonyms
Fmoc-3,5-dinitro-L-Tyr-OH, Fmoc-3,5-dinitro-4-hydroxy-L-phénylalanine
CAS Number
195434-42-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H19N3O9
Molecular Weight
493.39
MDL Number
MFCD02259488
PubChem ID
19706517
Melting Point
166-173 ?C
Appearance
Poudre jaune
Optical Rotation
[a] D 20 = -35 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Fmoc-3,5-dinitro-L-Tyr-OH, Fmoc-3,5-dinitro-4-hydroxy-L-phénylalanine
CAS Number
195434-42-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H19N3O9
Molecular Weight
493.39
MDL Number
MFCD02259488
PubChem ID
19706517
Melting Point
166-173 ?C
Appearance
Poudre jaune
Optical Rotation
[a] D 20 = -35 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3,5-dinitro-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex peptide sequences efficiently.
  • Drug Development: Its unique structure allows for the incorporation of dinitrophenyl groups, which can enhance the biological activity of pharmaceutical compounds, making it valuable in the development of new drugs.
  • Bioconjugation: The reactive sites on Fmoc-3,5-dinitro-L-tyrosine facilitate bioconjugation processes, where it can be linked to other biomolecules, aiding in the creation of targeted drug delivery systems.
  • Analytical Chemistry: This compound is used in various analytical methods, including HPLC and mass spectrometry, to study protein interactions and modifications, providing insights into biochemical pathways.
  • Research in Immunology: Its dinitrophenyl moiety can act as a hapten in immunological studies, helping researchers understand immune responses and develop vaccines or diagnostics.

Citations