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Catalog Number:
07052
CAS Number:
183070-44-2
Fmoc-(4- tert -butyloxycarbonyl)-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Phe(4-COOtBu)-OH, Fmoc-(4-carboxy- tert -butyl)-L-phénylalanine
Documents
$85.60 /100 mg
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Product Information

Fmoc-(4-tert-butyloxycarbonyl)-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the efficient coupling of amino acids, making it a preferred choice for researchers in the field of medicinal chemistry and biochemistry.

The tert-butyloxycarbonyl (Boc) group provides additional protection, allowing for greater control during the synthesis process. This compound is particularly valuable in the production of peptide-based therapeutics, where precision and purity are paramount. Its application extends to the development of novel drug candidates, where it aids in the formation of complex peptide structures. Researchers appreciate its ability to streamline synthesis while maintaining high yields and purity, making it an essential tool in the arsenal of peptide chemists.

Synonyms
Fmoc-L-Phe(4-COOtBu)-OH, Fmoc-(4-carboxy- tert -butyl)-L-phénylalanine
CAS Number
183070-44-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C 29 H 296
Molecular Weight
487.56
MDL Number
MFCD01317016
PubChem ID
18467948
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = 22,4 ± 2 ° (C=1 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(4-COOtBu)-OH, Fmoc-(4-carboxy- tert -butyl)-L-phénylalanine
CAS Number
183070-44-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C 29 H 296
Molecular Weight
487.56
MDL Number
MFCD01317016
PubChem ID
18467948
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = 22,4 ± 2 ° (C=1 dans CHCl 3 )
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(4-tert-butyloxycarbonyl)-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, enhancing bioavailability and stability.
  • Bioconjugation: The compound is used in bioconjugation processes, linking peptides to other molecules such as antibodies or drugs, which is essential for targeted therapies.
  • Research in Protein Engineering: It aids in the design of novel proteins with specific functionalities, making it valuable in biotechnology and synthetic biology.
  • Analytical Chemistry: This chemical is employed in the analysis of peptide structures and functions, providing insights into molecular interactions and mechanisms.

Citations