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Catalog Number:
05728
CAS Number:
71989-25-8
Ester de 4-nitrophényle de Fmoc-L-leucine
Purity:
≥ 99 % (CCM)
Synonym(s):
Fmoc-L-Leu-ONp, ( S)-Fmoc -2-amino-4-méthyl-pentanoïque acide 4-nitrophénylester
Documents
$29.34 /1G
Taille
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Informations sur le produit

Fmoc-L-leucine 4-nitrophenyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound serves as a protective group for the amino acid leucine, enabling chemists to selectively modify or couple it during the synthesis of complex peptides. Its unique structure, featuring the Fmoc (9-fluorenylmethoxycarbonyl) group, provides excellent stability under basic conditions while allowing for easy removal under mild acidic conditions, making it an ideal choice for researchers looking to streamline their synthesis processes.

In addition to its role in peptide synthesis, Fmoc-L-leucine 4-nitrophenyl ester is also employed in the development of pharmaceutical compounds, particularly in the creation of biologically active peptides. Its ability to enhance solubility and stability of peptide chains can lead to improved bioavailability and efficacy of therapeutic agents. Researchers in medicinal chemistry and biochemistry will find this compound invaluable for its efficiency and effectiveness in producing high-quality peptides for various applications, including drug discovery and development.

Numéro CAS 
71989-25-8
Formule moléculaire
C27H26N2O6
Poids moléculaire 
474.51
Point de fusion 
114-120 ?C
Rotation optique 
[a] D 24 = -48 ± 2º (C = 1 % dans le diméthylformamide et 1 % dans l'acide acétique)
Informations générales
Numéro CAS 
71989-25-8
Formule moléculaire
C27H26N2O6
Poids moléculaire 
474.51
Point de fusion 
114-120 ?C
Rotation optique 
[a] D 24 = -48 ± 2º (C = 1 % dans le diméthylformamide et 1 % dans l'acide acétique)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-L-leucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It is used in the development of peptide-based drugs, providing a means to modify peptide structures for enhanced therapeutic effects.
  • Bioconjugation: The compound facilitates the attachment of peptides to other biomolecules, which is crucial in creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the study of protein interactions and modifications, helping scientists understand protein functions and develop novel proteins.
  • Analytical Chemistry: Fmoc-L-leucine 4-nitrophenyl ester is employed in various analytical techniques, including chromatography, to analyze peptide compositions and purities.

Citations