Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
05723
CAS Number:
167015-23-8
Fmoc- S -trityl-L-homocystéine
Purity:
≥ 97 % (HPLC)
Synonym(s):
Fmoc-L-HomoCys(Trt)-OH, Acide ( S )-2-(Fmoc-amino)-4-tritylsulfanyl-butyrique
Documents
$115.70 /250 mg
Taille
Request Bulk Quote
Product Information

Fmoc-S-trityl-L-homocysteine is a valuable compound widely utilized in peptide synthesis and biochemistry. This derivative of homocysteine features a fluorenylmethoxycarbonyl (Fmoc) protecting group and a trityl (Tr) group, making it an essential building block for the synthesis of peptides and proteins. Its unique structure allows for selective protection of the amino group, facilitating the development of complex peptide sequences. Researchers appreciate its stability under various reaction conditions, which enhances its utility in solid-phase peptide synthesis (SPPS) and other synthetic methodologies.

In addition to its role in peptide synthesis, Fmoc-S-trityl-L-homocysteine has potential applications in drug discovery and development, particularly in the design of therapeutics targeting specific biological pathways. Its ability to form disulfide bonds can be leveraged in the creation of cyclic peptides, which are known for their enhanced stability and bioactivity. This compound is particularly advantageous for researchers looking to explore novel peptide-based drugs or study protein interactions, making it a versatile addition to any laboratory focused on peptide chemistry.

Synonyms
Fmoc-L-HomoCys(Trt)-OH, Acide ( S )-2-(Fmoc-amino)-4-tritylsulfanyl-butyrique
CAS Number
167015-23-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C 38 H 33 NON 4 S
Molecular Weight
599.74
MDL Number
MFCD00672322
PubChem ID
53395531
Melting Point
68 - 78 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 25 = 16 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-L-HomoCys(Trt)-OH, Acide ( S )-2-(Fmoc-amino)-4-tritylsulfanyl-butyrique
CAS Number
167015-23-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C 38 H 33 NON 4 S
Molecular Weight
599.74
MDL Number
MFCD00672322
PubChem ID
53395531
Melting Point
68 - 78 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 25 = 16 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-S-trityl-L-homocysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures.
  • Drug Development: It is used in the development of novel therapeutics, especially in the design of drugs targeting specific biological pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: The compound facilitates bioconjugation processes, enabling the attachment of various biomolecules to peptides, which is crucial for creating targeted drug delivery systems.
  • Research in Proteomics: It plays a significant role in proteomics research, aiding in the study of protein interactions and functions, which is essential for understanding disease mechanisms.
  • Antioxidant Studies: Fmoc-S-trityl-L-homocysteine is explored for its potential antioxidant properties, contributing to research aimed at mitigating oxidative stress in various biological systems.

Citations