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Catalog Number:
05584
CAS Number:
79561-25-4
Boc-4-fluoro-DL-phénylalanine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Boc-DL-Phe(4-F)-OH, Boc- p -fluoro-DL-Phe-OH, ( Acide RS -Boc-2-amino-3-(4-fluorophényl)propionique
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Product Information

Boc-4-fluoro-DL-phenylalanine is a versatile amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound features a unique 4-fluorophenyl group, which enhances its utility in medicinal chemistry, particularly in the design of novel therapeutics. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection during synthetic procedures, making it an ideal choice for researchers focused on complex peptide structures.

In pharmaceutical research, Boc-4-fluoro-DL-phenylalanine is utilized in the development of peptide-based drugs, where the fluorine atom can influence the compound's biological activity and pharmacokinetics. This characteristic makes it particularly valuable in the creation of targeted therapies, such as those aimed at specific receptors or enzymes. Its application extends to the production of biologically active compounds, where it can serve as a building block for various peptide sequences. Researchers and industry professionals will find this compound essential for advancing their projects in drug discovery and development.

Synonyms
Boc-DL-Phe(4-F)-OH, Boc- p -fluoro-DL-Phe-OH, ( Acide RS -Boc-2-amino-3-(4-fluorophényl)propionique
CAS Number
79561-25-4
Purity
≥ 99 % (HPLC)
Molecular Formula
C 14 H 18 FNO 4
Molecular Weight
283.2
MDL Number
MFCD00237573
PubChem ID
2756794
Melting Point
131-137 ?C
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Boc-DL-Phe(4-F)-OH, Boc- p -fluoro-DL-Phe-OH, ( Acide RS -Boc-2-amino-3-(4-fluorophényl)propionique
CAS Number
79561-25-4
Purity
≥ 99 % (HPLC)
Molecular Formula
C 14 H 18 FNO 4
Molecular Weight
283.2
MDL Number
MFCD00237573
PubChem ID
2756794
Melting Point
131-137 ?C
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-4-fluoro-DL-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in creating modified peptides with enhanced properties for drug development.
  • Drug Design: Its unique fluorine substitution allows researchers to explore new drug candidates with improved pharmacokinetics and bioavailability, making it valuable in pharmaceutical research.
  • Bioconjugation: The compound can be used in bioconjugation techniques, where it helps attach drugs or imaging agents to proteins, aiding in targeted therapy and diagnostics.
  • Research on Protein Folding: It plays a role in studies investigating protein folding and stability, providing insights into protein structure-function relationships that are crucial in biotechnology.
  • Fluorinated Amino Acids in Metabolic Studies: The incorporation of this fluorinated amino acid into proteins allows for metabolic tracing studies, helping researchers understand metabolic pathways in various biological systems.

Citations