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Catalog Number:
05538
CAS Number:
83468-80-8
Chlorhydrate d'ester méthylique de boc -N -p-benzyloxyméthyl-L-histidine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-His(3-BOM)-OMe·HCl, Boc-L-His(p-BOM)-OMe·HCl
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Product Information

Boc-N-p-benzyloxymethyl-L-histidine methyl ester hydrochloride is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected amino acid derivative features a benzyloxymethyl group, enhancing its stability and reactivity, making it an ideal choice for researchers focused on developing novel therapeutic peptides. Its unique structure allows for selective reactions, facilitating the introduction of various functional groups, which is crucial in the design of complex biomolecules.

In the pharmaceutical industry, Boc-N-p-benzyloxymethyl-L-histidine methyl ester hydrochloride is particularly valuable in the synthesis of bioactive peptides and drug candidates, offering improved solubility and bioavailability. Its applications extend to the development of targeted therapies, where precision in molecular design is paramount. Researchers appreciate its ease of use and compatibility with various coupling reagents, streamlining the synthesis process while ensuring high yields. This compound stands out for its ability to enhance the efficiency of peptide synthesis, making it a preferred choice for professionals aiming to innovate in drug development.

Synonyms
Boc-His(3-BOM)-OMe·HCl, Boc-L-His(p-BOM)-OMe·HCl
CAS Number
83468-80-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C20H27N3O5 · HCl
Molecular Weight
425.59
MDL Number
MFCD00076941
PubChem ID
91979034
Melting Point
138-143 ºC
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0-8°C
General Information
Synonyms
Boc-His(3-BOM)-OMe·HCl, Boc-L-His(p-BOM)-OMe·HCl
CAS Number
83468-80-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C20H27N3O5 · HCl
Molecular Weight
425.59
MDL Number
MFCD00076941
PubChem ID
91979034
Melting Point
138-143 ºC
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-N-p-benzyloxymethyl-L-histidine methyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others, thus enhancing the efficiency of peptide production.
  • Drug Development: It is used in the design of new pharmaceuticals, particularly in creating compounds that target specific biological pathways, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The chemical plays a role in attaching biomolecules to surfaces or other molecules, which is crucial in developing diagnostic tools and targeted drug delivery systems.
  • Research in Cancer Therapy: Its application in the development of histidine-containing compounds is significant in cancer research, as these compounds can be designed to interact with tumor cells selectively.
  • Protein Engineering: This compound aids in modifying proteins for various applications, such as improving stability or functionality, which is essential in biotechnology and therapeutic development.

Citations