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Catalog Number:
05490
CAS Number:
214630-10-1
Ester α-9-fluorénylméthylique de l'acide boc-D-glutamique
Purity:
≥ 98 % (dosage)
Synonym(s):
Boc-D-Glu-OFm
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Product Information

Boc-D-glutamic acid a-9-fluorenylmethyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of D-glutamic acid features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and reactivity during chemical reactions. The incorporation of the 9-fluorenylmethyl ester moiety not only improves solubility but also facilitates the purification of peptides, making it an essential building block for researchers in the field of medicinal chemistry.

This compound is particularly valuable in the synthesis of bioactive peptides and can be employed in various applications, including drug development and the creation of novel therapeutic agents. Its unique structure allows for selective reactions, which can lead to the formation of complex peptide sequences with high specificity. Researchers benefit from its ease of use and the efficiency it brings to synthetic pathways, making Boc-D-glutamic acid a-9-fluorenylmethyl ester a preferred choice for those aiming to streamline their peptide synthesis processes.

Synonyms
Boc-D-Glu-OFm
CAS Number
214630-10-1
Purity
≥ 98 % (dosage)
Molecular Formula
C 24 H 276
Molecular Weight
425.48
MDL Number
MFCD00798626
PubChem ID
4712640
Melting Point
96 - 100 °C (lit.)
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 43 ± 2 (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Boc-D-Glu-OFm
CAS Number
214630-10-1
Purity
≥ 98 % (dosage)
Molecular Formula
C 24 H 276
Molecular Weight
425.48
MDL Number
MFCD00798626
PubChem ID
4712640
Melting Point
96 - 100 °C (lit.)
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 43 ± 2 (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-D-glutamic acid a-9-fluorenylmethyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is particularly useful in the pharmaceutical industry for developing new drugs.
  • Drug Development: Its role in modifying amino acids can enhance the bioavailability and stability of therapeutic agents, making it valuable in the formulation of more effective medications.
  • Bioconjugation: The compound can be used in bioconjugation processes to attach drugs or imaging agents to biomolecules, facilitating targeted therapies in cancer treatment.
  • Research in Neuroscience: By providing a stable form of glutamic acid, it aids in studying neurotransmitter functions and their implications in neurological disorders, helping researchers develop better treatment strategies.
  • Polymer Chemistry: Its derivatives can be incorporated into polymer matrices, enhancing properties such as solubility and mechanical strength, which is beneficial in materials science applications.

Citations