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Catalog Number:
05459
CAS Number:
42002-18-6
Ester de N α - Boc-L-asparagine N -hydroxysuccinimide
Purity:
≥ 99 % (CCM)
Synonym(s):
Boc-L-Asn-OSu
Documents
$180.00 /1G
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Informations sur le produit

Na-Boc-L-asparagine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which is crucial for the selective protection of amino acids during synthetic processes. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focused on developing complex peptides and proteins. The N-hydroxysuccinimide ester functionality enhances the reactivity of the asparagine residue, facilitating the formation of stable amide bonds with various nucleophiles, including amino acids and peptides.

This compound is particularly beneficial in the pharmaceutical and biotechnology industries, where it can be employed in the design of therapeutic peptides and drug delivery systems. Its ability to improve solubility and stability of peptide constructs makes it a valuable tool for researchers aiming to optimize the pharmacokinetic properties of their compounds. Additionally, Na-Boc-L-asparagine N-hydroxysuccinimide ester stands out for its compatibility with a range of reaction conditions, providing flexibility in synthetic strategies.

Numéro CAS 
42002-18-6
Formule moléculaire
C13H19N3O7
Poids moléculaire 
329.31
Rotation optique 
[a] D 24 = -33,1 ± 2º (C = 1 % dans l'acétone)
Informations générales
Numéro CAS 
42002-18-6
Formule moléculaire
C13H19N3O7
Poids moléculaire 
329.31
Rotation optique 
[a] D 24 = -33,1 ± 2º (C = 1 % dans l'acétone)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
-
Applications

Na-Boc-L-asparagine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create complex structures with specific amino acid sequences for various applications in drug development.
  • Bioconjugation: It is used in bioconjugation processes, where it helps to link biomolecules, such as proteins and antibodies, to therapeutic agents, enhancing the efficacy of targeted drug delivery systems.
  • Protein Modification: The ester functionality allows for selective modification of proteins, which can be crucial in studying protein interactions and functions, thereby aiding in the development of new therapeutic strategies.
  • Diagnostic Applications: This compound can be employed in the development of diagnostic assays, particularly in the field of immunology, where it helps in the labeling of antigens or antibodies for detection purposes.
  • Research in Neuroscience: It is also used in neuroscience research to study the role of asparagine in neurotransmission, providing insights into potential treatments for neurological disorders.

Citations