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Catalog Number:
05347
CAS Number:
134486-00-3
Fmoc-3-iodo-L-tyrosine
Purity:
≥ 97,5 % (HPLC)
Synonym(s):
Fmoc-3-IL-Tyr-OH, Fmoc-3-IL-Phe(4-OH)-OH
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$160.00 /1G
Taille
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Informations sur le produit

Fmoc-3-iodo-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, incorporating an iodine atom, enhances its reactivity and makes it a valuable building block for the development of biologically active compounds. Researchers appreciate its application in the synthesis of peptide-based drugs and in the study of protein interactions, where the iodine substitution can facilitate various analytical techniques, such as NMR and mass spectrometry.

In addition to its role in peptide synthesis, Fmoc-3-iodo-L-tyrosine is also significant in the field of drug discovery, particularly for the development of targeted therapies. Its ability to serve as a precursor for the introduction of iodine into peptide sequences can lead to the creation of novel compounds with enhanced therapeutic properties. This compound is particularly advantageous for researchers looking to explore the structure-activity relationship (SAR) of peptides, providing a pathway to innovate in the design of new pharmaceuticals.

Numéro CAS 
134486-00-3
Formule moléculaire
C 24 H 205 I
Poids moléculaire 
529.2
Rotation optique 
[a] D 20 = -11 ± 2º (C = 1 dans DMF)
Informations générales
Numéro CAS 
134486-00-3
Formule moléculaire
C 24 H 205 I
Poids moléculaire 
529.2
Rotation optique 
[a] D 20 = -11 ± 2º (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-3-iodo-L-tyrosine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of iodine, which can be useful for labeling or further functionalization.
  • Drug Development: It is employed in the design of novel pharmaceuticals, especially in the development of targeted therapies where iodine can enhance the biological activity of drug candidates.
  • Bioconjugation: The unique properties of this compound facilitate bioconjugation processes, enabling researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Imaging Techniques: Its iodine content makes it suitable for use in imaging applications, such as in the development of radiolabeled compounds for diagnostic purposes in medical imaging.
  • Research in Neuroscience: The compound is useful in neuroscience research, particularly in studying receptor interactions and signaling pathways, due to its structural similarity to neurotransmitters.

Citations