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Catalog Number:
05129
CAS Number:
198475-65-9
Boc-4-(2-chloro-Z-amino)-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-L-Phe(4-NH-2-CL-Z)-OH
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Product Information

Boc-4-(2-chloro-Z-amino)-L-phenylalanine is a versatile amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued for its ability to introduce specific functionalities into peptides, making it an essential building block for researchers in medicinal chemistry and biochemistry. Its unique structure, featuring a Boc (tert-butyloxycarbonyl) protecting group and a chloro substituent, enhances its reactivity and stability, allowing for selective modifications in complex synthetic pathways.

In practical applications, Boc-4-(2-chloro-Z-amino)-L-phenylalanine is utilized in the development of peptide-based therapeutics, particularly in the design of inhibitors and biologically active compounds. Its properties facilitate the creation of peptides with improved bioavailability and specificity, which are crucial in pharmaceutical formulations. Researchers appreciate its compatibility with various coupling reactions, enabling efficient synthesis of diverse peptide sequences. This compound not only streamlines the synthesis process but also opens avenues for innovative drug design, making it a valuable asset in both academic and industrial settings.

Synonyms
Boc-L-Phe(4-NH-2-CL-Z)-OH
CAS Number
198475-65-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C22H25N2O8Cl
Molecular Weight
299.7
MDL Number
MFCD01075088
PubChem ID
75627283
Appearance
Solide cristallin blanc cassé
Optical Rotation
[a] 26 D = 12 ± 1 ° (C = 2,49 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Boc-L-Phe(4-NH-2-CL-Z)-OH
CAS Number
198475-65-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C22H25N2O8Cl
Molecular Weight
299.7
MDL Number
MFCD01075088
PubChem ID
75627283
Appearance
Solide cristallin blanc cassé
Optical Rotation
[a] 26 D = 12 ± 1 ° (C = 2,49 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-4-(2-chloro-Z-amino)-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, facilitating the creation of complex structures for pharmaceutical development.
  • Drug Development: It plays a significant role in the design of novel therapeutics, particularly in targeting specific biological pathways, making it valuable in the pharmaceutical industry.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs to antibodies or other biomolecules, enhancing drug delivery systems.
  • Research in Cancer Therapy: Its unique properties allow researchers to explore new avenues in cancer treatment, particularly in developing targeted therapies that minimize side effects.
  • Protein Engineering: This chemical is instrumental in modifying proteins to improve their stability and functionality, which is crucial in biotechnological applications.

Citations