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Catalog Number:
05021
CAS Number:
169555-95-7
Fmoc-3-(4'-pyridyl)-L-alanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Ala(4'-pyridyl)-OH, Fmoc-β-(4'-pyridyl)-Ala-OH, Acide Fmoc-( S )-2-amino-3-(4'-pyridyl)propanoïque
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Informations sur le produit

Fmoc-3-(4'-pyridyl)-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique pyridyl side chain enhances the compound's ability to participate in various chemical reactions, making it a valuable building block for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-3-(4'-pyridyl)-L-alanine is particularly beneficial in the development of peptide-based therapeutics, where its structural properties can influence the biological activity of the resulting peptides. Its stability and compatibility with standard coupling reagents allow for efficient incorporation into peptide sequences, facilitating the exploration of novel therapeutic agents. Researchers appreciate its ability to improve solubility and bioavailability in drug formulations, making it an essential component in the design of effective pharmaceutical compounds.

Numéro CAS 
169555-95-7
Formule moléculaire
C23H20N2O4
Poids moléculaire 
388.4
Point de fusion 
198 - 203 °C (lit.)
Rotation optique 
[a] D 20
Informations générales
Numéro CAS 
169555-95-7
Formule moléculaire
C23H20N2O4
Poids moléculaire 
388.4
Point de fusion 
198 - 203 °C (lit.)
Rotation optique 
[a] D 20
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-3-(4'-pyridyl)-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: The unique structure enhances the bioactivity of peptide-based drugs, making it valuable in pharmaceutical research aimed at developing new therapeutics.
  • Bioconjugation: It is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Diagnostics: The compound's properties are leveraged in the design of diagnostic tools, particularly in assays that require specific interactions with biological targets.
  • Material Science: In the field of material science, it is applied in creating functional materials that can respond to environmental stimuli, which is useful in sensors and smart materials.

Citations