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Catalog Number:
05013
CAS Number:
61280-75-9
Boc-4-nitro-D-phénylalanine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Boc-D-Phe(4-NO2)-OH, Boc- p -nitro-D-Phe-OH
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Product Information

Boc-4-nitro-D-phenylalanine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its unique nitro group provides additional reactivity, allowing for selective modifications that can lead to the development of novel therapeutic agents.

In practical applications, Boc-4-nitro-D-phenylalanine is utilized in the synthesis of bioactive peptides, which are essential in pharmaceuticals and biotechnology. Its ability to facilitate the introduction of specific functional groups makes it a valuable tool for creating compounds with targeted biological activities. Researchers appreciate its compatibility with various coupling reactions, which streamlines the process of peptide assembly. This compound not only enhances the efficiency of synthetic pathways but also opens avenues for the exploration of new drug candidates with improved efficacy and selectivity.

Synonyms
Boc-D-Phe(4-NO2)-OH, Boc- p -nitro-D-Phe-OH
CAS Number
61280-75-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.3
MDL Number
MFCD00069880
PubChem ID
118071
Melting Point
107-120 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -8 ± 1,5º (C = 1 % dans MeOH) D 20 = +32 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Boc-D-Phe(4-NO2)-OH, Boc- p -nitro-D-Phe-OH
CAS Number
61280-75-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.3
MDL Number
MFCD00069880
PubChem ID
118071
Melting Point
107-120 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -8 ± 1,5º (C = 1 % dans MeOH) D 20 = +32 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-4-nitro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting other functional groups.
  • Drug Development: It is used in the design of pharmaceutical compounds, particularly in creating drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving drug delivery systems.
  • Research in Neurobiology: Its application in studying neurotransmitter interactions provides insights into neurological disorders, aiding in the development of targeted treatments.
  • Analytical Chemistry: Boc-4-nitro-D-phenylalanine is utilized as a standard in analytical methods, helping researchers quantify and analyze related compounds more accurately.

Citations