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Catalog Number:
04989
CAS Number:
146998-27-8
N α -Fmoc- N ε -diméthylaminophényldiazobenzoyl-L-lysine
Purity:
≥ 97 % (HPLC)
Synonym(s):
Fmoc-L-Lys(Dabcyl)-OH
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$95.60 /250 mg
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Product Information

Na-Fmoc-Ne-dimethylaminophenyldiazobenzoyl-L-lysine is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a unique structure that combines the protective Fmoc group with a diazo-benzoyl moiety, making it an excellent choice for researchers looking to enhance the stability and solubility of peptides during synthesis. Its ability to facilitate selective reactions allows for the efficient incorporation of functional groups, which is crucial in the development of novel therapeutics and diagnostic tools.

In addition to its role in peptide chemistry, Na-Fmoc-Ne-dimethylaminophenyldiazobenzoyl-L-lysine is also valuable in the field of drug delivery systems, where it can be employed to create targeted delivery vehicles. The compound's properties enable it to improve the pharmacokinetics of drug candidates, enhancing their efficacy and reducing side effects. Researchers in medicinal chemistry and biochemistry will find this compound particularly beneficial for advancing their projects, given its unique features and practical applications in drug development and peptide research.

Synonyms
Fmoc-L-Lys(Dabcyl)-OH
CAS Number
146998-27-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C36H37N5O5
Molecular Weight
619.7
MDL Number
MFCD00467694
PubChem ID
3484914
Appearance
Poudre cristalline rouge orangée
Optical Rotation
[a] 20 D = 18 - 27 ° (C = 0,1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Dabcyl)-OH
CAS Number
146998-27-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C36H37N5O5
Molecular Weight
619.7
MDL Number
MFCD00467694
PubChem ID
3484914
Appearance
Poudre cristalline rouge orangée
Optical Rotation
[a] 20 D = 18 - 27 ° (C = 0,1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Na-Fmoc-Ne-dimethylaminophenyldiazobenzoyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing for the selective modification of amino acids. Its use helps streamline the process, making it easier to create complex peptides.
  • Drug Development: In pharmaceutical research, it aids in the design of novel drug candidates by facilitating the incorporation of specific amino acid sequences, which can enhance the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, linking biomolecules to create targeted drug delivery systems. This application is particularly relevant in cancer therapy, where precision is crucial.
  • Fluorescent Labeling: It can be used for fluorescent labeling of peptides, enabling researchers to track and visualize biological processes in real-time, which is essential in cellular biology studies.
  • Protein Engineering: This chemical plays a role in protein engineering, allowing scientists to modify protein structures for improved stability and functionality, which is vital in developing enzymes and therapeutic proteins.

Citations