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Catalog Number:
04133
CAS Number:
201484-50-6
Fmoc-3,3-diphényl-L-alanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Ala(3,3-diphényl)-OH, ( S )- N -(Fmoc)-β-phényl-phénylalanine, Fmoc-Ala(3,3-diphényl)-OH
Hazmat
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Product Information

Fmoc-3,3-diphenyl-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of two phenyl groups, enhances its stability and solubility, making it an excellent choice for researchers focused on developing complex peptide sequences.

In practical applications, Fmoc-3,3-diphenyl-L-alanine is often employed in solid-phase peptide synthesis (SPPS), facilitating the creation of peptides with high purity and yield. Its ability to provide steric hindrance allows for the synthesis of peptides that may otherwise be challenging to produce. Additionally, this compound has shown potential in the development of pharmaceuticals, particularly in designing peptide-based drugs that target specific biological pathways. Researchers and industry professionals can leverage its properties to streamline their synthesis processes and enhance the efficacy of their peptide-based applications.

Synonyms
Fmoc-L-Ala(3,3-diphényl)-OH, ( S )- N -(Fmoc)-β-phényl-phénylalanine, Fmoc-Ala(3,3-diphényl)-OH
CAS Number
201484-50-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 30 H 254
Molecular Weight
463.5
MDL Number
MFCD00672337
PubChem ID
3629137
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] 20 D = -24 ± 4 º (C=1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Warnings
Avertissement.
General Information
Synonyms
Fmoc-L-Ala(3,3-diphényl)-OH, ( S )- N -(Fmoc)-β-phényl-phénylalanine, Fmoc-Ala(3,3-diphényl)-OH
CAS Number
201484-50-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 30 H 254
Molecular Weight
463.5
MDL Number
MFCD00672337
PubChem ID
3629137
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] 20 D = -24 ± 4 º (C=1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Warnings
Avertissement.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
Avertissement.
Applications

Fmoc-3,3-diphenyl-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: Researchers use it for attaching peptides to various biomolecules, facilitating the development of targeted drug delivery systems.
  • Analytical Chemistry: The compound is employed in the characterization of peptides and proteins, aiding in the understanding of their structure and function.
  • Material Science: It is explored in creating novel materials with specific properties, such as improved mechanical strength or biocompatibility, for applications in biomedical devices.

Citations