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Catalog Number:
04127
CAS Number:
205526-24-5
Fmoc-3,5-difluoro-L-phénylalanine
Purity:
≥ 97 % (HPLC)
Synonym(s):
Fmoc-L-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-L-Phe-OH
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$68.90 /250 mg
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Product Information

Fmoc-3,5-difluoro-L-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique difluorophenyl group that enhances its biochemical properties, making it an excellent choice for researchers looking to create fluorinated peptides with improved stability and bioactivity. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, facilitating the synthesis of complex structures that are crucial in pharmaceutical research and development.

In addition to its role in peptide synthesis, Fmoc-3,5-difluoro-L-phenylalanine is particularly beneficial in the study of protein interactions and enzyme activity due to its fluorinated structure, which can provide insights into molecular behavior and binding affinities. This compound is essential for researchers in medicinal chemistry and biochemistry, offering a pathway to develop novel therapeutics with enhanced efficacy. Its unique properties set it apart from similar compounds, making it a preferred choice for professionals aiming to innovate in the field of peptide-based drug design.

Synonyms
Fmoc-L-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-L-Phe-OH
CAS Number
205526-24-5
Purity
≥ 97 % (HPLC)
Molecular Formula
C 24 H 19 F 2 NON 4
Molecular Weight
423.4
MDL Number
MFCD00797579
PubChem ID
53394996
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -43 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-L-Phe-OH
CAS Number
205526-24-5
Purity
≥ 97 % (HPLC)
Molecular Formula
C 24 H 19 F 2 NON 4
Molecular Weight
423.4
MDL Number
MFCD00797579
PubChem ID
53394996
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -43 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3,5-difluoro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its unique fluorinated structure enhances the stability and bioactivity of the resulting peptides.
  • Drug Development: Researchers leverage its properties to design and develop novel pharmaceuticals, especially in targeting specific receptors due to its ability to modify binding interactions.
  • Bioconjugation: The compound is used in bioconjugation techniques, allowing for the attachment of biomolecules to peptides, which is crucial in creating targeted drug delivery systems.
  • Fluorine-Containing Compounds: Its incorporation into various compounds is valuable in medicinal chemistry, as fluorine can enhance metabolic stability and bioavailability of drugs.
  • Research in Protein Engineering: This chemical aids in the study of protein folding and stability, providing insights into the design of more effective therapeutic proteins.

Citations