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Catalog Number:
04035
CAS Number:
132388-68-2
N α - Boc- N γ -trityl-L-asparagine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-L-Asn(Trt)-OH
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Informations sur le produit

Na-Boc-Ng-trityl-L-asparagine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and reactivity, making it an ideal choice for the synthesis of complex peptides. Its unique trityl group provides additional protection for the amino group, facilitating selective reactions and improving yields in various synthetic pathways. Researchers appreciate its role in the development of bioactive peptides and therapeutic agents, particularly in the fields of drug discovery and development.

The compound's ability to undergo selective deprotection allows for the strategic assembly of peptides with specific functionalities, enabling the exploration of structure-activity relationships in medicinal chemistry. Na-Boc-Ng-trityl-L-asparagine is especially valuable in the synthesis of peptide-based drugs and can be employed in the production of peptide libraries for high-throughput screening. Its favorable properties and compatibility with various coupling reagents make it a preferred choice for chemists aiming to optimize peptide synthesis processes.

Numéro CAS 
132388-68-2
Formule moléculaire
C28H30N2O5
Poids moléculaire 
474.6
Point de fusion 
180 - 200 ?C
Rotation optique 
[a] D 20 = -20 ± 2 º (C = 1 dans MeOH)
Informations générales
Numéro CAS 
132388-68-2
Formule moléculaire
C28H30N2O5
Poids moléculaire 
474.6
Point de fusion 
180 - 200 ?C
Rotation optique 
[a] D 20 = -20 ± 2 º (C = 1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
-
Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
-
Applications

Na-Boc-Ng-trityl-L-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others, thus streamlining the production of complex peptides.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in the design of novel therapeutics that target specific biological pathways, enhancing drug efficacy.
  • Bioconjugation: Researchers use it for bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents, improving the specificity and effectiveness of treatments.
  • Protein Engineering: The compound is essential in protein engineering, allowing scientists to create modified proteins with enhanced stability and activity for various applications, including enzyme design.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter signaling, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.

Citations