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Catalog Number:
03987
CAS Number:
2488-14-4
Ester méthylique de N a - Boc-L-histidine
Purity:
≥ 99 % (CCM)
Synonym(s):
Boc-L-His-OMe
Documents
$51.18 /1G
Taille
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Informations sur le produit

Na-Boc-L-histidine methyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of histidine features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for various applications in organic synthesis. Researchers often leverage its unique properties to facilitate the formation of complex peptide structures, particularly in the development of biologically active compounds and drug candidates. Its imidazole side chain contributes to its role in enzyme catalysis and metal ion coordination, further expanding its utility in biochemical studies.

In addition to its applications in synthetic chemistry, Na-Boc-L-histidine methyl ester is also valuable in the field of medicinal chemistry, where it serves as a building block for the synthesis of histidine-containing peptides and proteins. The compound's favorable solubility and compatibility with various reaction conditions make it a preferred choice among researchers looking to explore the therapeutic potential of histidine derivatives. With its broad range of applications, Na-Boc-L-histidine methyl ester stands out as a crucial tool for advancing research in peptide chemistry and drug development.

Numéro CAS 
2488-14-4
Formule moléculaire
C12H19N3O4
Poids moléculaire 
269.3
Point de fusion 
121-128 ºC
Informations générales
Numéro CAS 
2488-14-4
Formule moléculaire
C12H19N3O4
Poids moléculaire 
269.3
Point de fusion 
121-128 ºC
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Na-Boc-L-histidine methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require histidine residues, enhancing the efficiency of creating complex biomolecules.
  • Drug Development: It plays a significant role in the design of pharmaceuticals, especially in developing histidine-containing drugs, which can improve solubility and bioavailability.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.
  • Protein Engineering: It aids in the modification of proteins to study their functions and interactions, providing insights that are vital for advancements in biotechnology and therapeutic applications.
  • Research on Enzyme Activity: This chemical is utilized in studies examining enzyme activity, particularly those involving histidine residues, helping to elucidate mechanisms of action and potential inhibitors.

Citations