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Catalog Number:
03976
CAS Number:
163679-35-4
Ester N- hydroxysuccinimide de boc-3,5-diiodo-L-tyrosine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-3,5-diiodo-L-Tyr-OSu
Documents
$96.34 /1G
Taille
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Informations sur le produit

Boc-3,5-diiodo-L-tyrosine N-hydroxysuccinimide ester is a specialized compound that plays a crucial role in bioconjugation and peptide synthesis. This compound is particularly valued in the fields of medicinal chemistry and pharmaceutical research due to its unique properties that facilitate the attachment of biomolecules. The presence of the Boc (tert-butyloxycarbonyl) protecting group allows for selective reactions, making it an excellent choice for researchers looking to modify peptides or proteins without compromising their integrity. Its diiodinated structure enhances its utility in imaging applications, particularly in radiolabeling studies, where it can be used to track biological processes in vivo.

In addition to its applications in research, Boc-3,5-diiodo-L-tyrosine N-hydroxysuccinimide ester is also beneficial in the development of targeted drug delivery systems. By conjugating this compound with therapeutic agents, researchers can improve the specificity and efficacy of treatments, particularly in oncology. Its ability to form stable linkages with various biomolecules makes it a versatile tool for scientists aiming to innovate in drug design and delivery. This compound stands out for its dual functionality, serving both as a building block for complex molecules and as a means to enhance the performance of existing therapeutic agents.

Numéro CAS 
163679-35-4
Formule moléculaire
C18H20I2N2O7
Poids moléculaire 
630.33
Point de fusion 
142-149 °C
Rotation optique 
[a] D 20 = +16 ± 2º (C=1 dans CHCl3)
Informations générales
Numéro CAS 
163679-35-4
Formule moléculaire
C18H20I2N2O7
Poids moléculaire 
630.33
Point de fusion 
142-149 °C
Rotation optique 
[a] D 20 = +16 ± 2º (C=1 dans CHCl3)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Boc-3,5-diiodo-L-tyrosine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly those that require specific modifications for enhanced stability or activity.
  • Drug Development: It is employed in the design of novel pharmaceuticals, especially in targeting thyroid-related conditions due to its iodine content, which can enhance the biological activity of drug candidates.
  • Bioconjugation: The N-hydroxysuccinimide ester functionality allows for efficient conjugation to proteins or antibodies, facilitating the development of targeted therapies and diagnostic agents.
  • Imaging Applications: Its unique properties make it suitable for use in radiolabeling techniques, which are essential in medical imaging and research, particularly in tracking biological processes in vivo.
  • Research in Thyroid Hormone Analogues: This compound is instrumental in studying thyroid hormone analogues, aiding researchers in understanding hormone interactions and developing treatments for thyroid disorders.

Citations