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Catalog Number:
03736
CAS Number:
158000-21-6
Ester de N- hydroxysuccinimide de Fmoc- O - tert -butyl-L-sérine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Ester N-hydroxysuccinimide de Fmoc-O-tert-butyl-L-sérine
Documents
$36.65 /1G
Taille
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Informations sur le produit

Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester is a versatile and valuable compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc group that facilitates the selective coupling of amino acids, making it an essential reagent for researchers in the fields of organic chemistry and biochemistry. Its unique structure allows for the efficient formation of peptide bonds while maintaining the integrity of the serine side chain, which is crucial for the synthesis of complex peptides and proteins.

The N-hydroxysuccinimide ester functionality enhances the reactivity of the compound, enabling it to readily react with amines to form stable amide bonds. This property is particularly beneficial in the development of peptide-based therapeutics and in the modification of biomolecules for drug delivery systems. Researchers appreciate its ease of use and the high purity it offers, which contributes to successful outcomes in various applications, including vaccine development and targeted drug delivery.

Numéro CAS 
158000-21-6
Formule moléculaire
C26H28N2O7
Poids moléculaire 
480.4
Point de fusion 
96-102 °C
Rotation optique 
[α] D 20 = -13 ± 2º (C = 1 dans DMF)
Informations générales
Numéro CAS 
158000-21-6
Formule moléculaire
C26H28N2O7
Poids moléculaire 
480.4
Point de fusion 
96-102 °C
Rotation optique 
[α] D 20 = -13 ± 2º (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with high specificity and efficiency.
  • Drug Development: It is used in the development of pharmaceutical compounds, particularly in creating targeted drug delivery systems that enhance therapeutic efficacy.
  • Bioconjugation: The chemical is effective in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Protein Engineering: It aids in modifying proteins to improve their stability and functionality, making it valuable in biotechnology and enzyme engineering.
  • Research in Cancer Therapy: This compound is explored in cancer research for its potential to improve the delivery of chemotherapeutic agents directly to tumor cells, enhancing treatment outcomes.

Citations